Estimands—What Do They Mean for Health Technology Assessment?


An estimand aims to clarify whether a clinical trial is actually measuring what we think/hope it is measuring.

While the ICH E9 revision focuses mainly on pre-approval activities and stakeholders, estimands will also play an important role in late phase.

Despite the current lack of clarity surrounding implementation, the HEOR community should welcome the revision.

Your browser is out-of-date

ISPOR recommends that you update your browser for more security, speed and the best experience on Update my browser now