To provide statistical leadership for strengthening the use of appropriate statistical methodology in health economics and outcomes research and improve the analytic techniques used in real world data analysis.


  • To review and recommend statistical methods used in outcomes research studies
  • To provide insight on the impact of using appropriate statistical methodology in a rigorous manner to enhance credible research
  • To better understand the limitations of analyses and methods used by the HEOR community


Statistics are used in many outcomes research studies, in which understanding the proper use of the methods and approaches that have been developed around certain types of analyses is crucial to producing reliable and valid results that may be reproducible to the rest of the research community. Appropriate application of statistics is the foundation of credible research.

To answer a number of research questions, there are various statistical methods used in real world data analysis such as multiplicity, Bayesian analyses, estimation in disease state changes, model averaging, machine learning/artificial intelligence, and causal inferences, to name a few. However, there are large gaps in the statistical knowledge base as it relates to real world data analysis including the effect of missing values in claims databases, their impact on analyses, and appropriate methods for imputation.



Shannon Cope, MSc

Senior Vice President, PRECISIONheor


Emma Hawe, MSc, BSc

Head, Data Analytics and Design Strategy, RTI Health Solutions
Manchester, LAN, United Kingdom

Past Chair

Helene Karcher, PhD

Novartis AG
Basel, BS, Switzerland

Operational Lead

Uzma Pathan

ISPOR Student Member, University of Maryland, Baltimore
Baltimore, MD, United States

Working Groups:

Member Engagement


Wai-kit Ming, PhD, MD, MPH

Assistant Professor / Program Leader, City University of Hong Kong
City University of Hong Kong, Hong Kong

Kumar Mukherjee, MS, PhD

Associate Director, Oncology Outcomes Research, AstraZeneca
Gaithersburg, MD, United States

Martin Scott, MSc, BSc

Director, Numerus
Reutlingen, Germany

Key Project

Under Development

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