Evidence of Quantitative Measures of Preferences Over Health States in Schizophrenia
Abstract
We are writing to inform readers of the results of 2 papers,referred to but not reported on in “Health State Utility Values in Schizophrenia: A Systematic Review and Meta-Analysis” by Aceituno and colleagues. Both papers employed the generic preference-based measure, the Assessment of Quality of Life (AQoL)-4D.
Herrman and colleagues determined the validity of the AQoL-4D in people with psychotic disorders (n = 173) while Neil and colleagues revealed the sensitivity of the instrument in a different group of people with psychotic disorders. In the latter, which covered a large, nationally representative population (n = 1613) and was one of the most comprehensive epidemiological studies internationally, marked variations in utilities were observed for key subjective and objective measures. Further, the profound impacts of psychotic illness on health-related quality of life were highlighted through an assessment of health inequalities compared with the general population in the distribution of utility values across 10 bands (decades) of the utility scale and by age. We also note a more recent study has found that the AQoL-4D can differentiate between functioning and social experiences, and that the perception of loneliness is particularly important to the HRQoL of people living with a psychotic disorder.
Authors
Amanda L. Neil Vaughan J. Carr Adriana G. Nevarez-Flores Helen Herrman Vera A. Morgan