Abstract

Health technology assessment (HTA) is rapidly evolving as new frontiers are added to existing ones. Its pace of evolution is remarkable even in the rapidly developing arena of the sciences. Major developments have taken place with HTA, specifically in methodology, as well as policymakers’ adoption of using HTA-generated evidence in resource allocation decisions. Some recent developments in methodology and policy are HTA usage for personalized medicine, conjoint analysis, mixed treatment comparison, use of real-world data, coverage with evidence development, risk-sharing scheme, and structured budget impact analysis.