To curate an ongoing dialog regarding issues around creating, disseminating, sharing, evaluating, and updating open source cost-effectiveness and comparative effectiveness models.


  • Define the issues surrounding open source models
  • Improve model transparency, updating, idea exchange, currency, and policy development
  • Provide a centralized platform to facilitate discussion and dissemination of information on the topic of open source models


The world is moving towards more openness, sharing, and collaboration. There has been a marked growth in open science; however, there is currently no efficient process for creating, sharing, evaluating, and updating health economic models. This situation can result in the expensive re-creation of existing models or the inappropriate use of outdated models. Moreover, models are often not updated at all. To address these issues, certain institutions have begun to promote and encourage access to open source models and some journals make models available to reviewers upon their request. However, it is unclear how these various groups will encourage widespread model openness and transparency in a repository or otherwise, given intellectual property (IP) rights, costs to initiate and sustain, and legal, information technology, and other issues surrounding such an endeavor. This Special Interest Group has therefore been founded to address these and other challenges and aspects related to the concept of open source models.



Xavier Pouwels, MSc

Postdoc, University of Twente
Enschede, OV, Netherlands


Raymond Henderson

Senior HTA Manager, Salutem Insights Ltd
Portlaoise, LS, Ireland

Past Chair

Christopher Sampson, MSc, BA

Principal Economist, Office of Health Economics
London, LON, United Kingdom

Working Groups

Member Engagement


Renée Arnold, PharmD, RPh

Icahn School of Medicine at Mount Sinai
New York, NY, United States

Ramesh Bhandari

Asst. Professor, KLE College of Pharmacy, KAHER, Belagavi
Belagavi, KA, India

Talitha Feenstra, PhD

Associate Professor, Groningen University/RIVM
Eelderwolde, DR, Netherlands

Ron Handels

assistant professor, Maastricht University
maastricht, LI, Netherlands

Stephanie Harvard

Postdoctoral Fellow, University of British Columbia
Vancouver, BC, Canada

Tim Wrightson, BSc

Editor, Applied Health Economics and Health Policy, PharmacoEconomics, Adis Journals
Auckland, AUK, New Zealand

Key Project

The Why, How, and Who of an Open-Source Future


Xavier Pouwels, MSc

Postdoc, University of Twente
Enschede, OV, Netherlands
Questions or ideas? Please send an email to opensourcesig@ISPOR.org
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