OBJECTIVES:: This study purpose to evaluate the economic impact NT-proBNP test to support the Heart Failure diagnosis and management of patients presenting dyspnea in the Emergency Department at Brazilian private payer perspective. METHODS:: An economic tool was developed based on peer-reviewed published data to compare the standard clinical assessment versus the clinical assessment guided by NT-proBNP test, the time horizon considered was 60 days. The direct medical costs were based on the CBHPM 2016 list (Classificação Brasileira Hierarquizada de Procedimentos Médicos). The one-way sensitivity analysis was performed with a variation of 20%, in which the best case scenario was developed with a reduction of 20% in all parameters and the worst case scenario with 20% increase on them. RESULTS:: The economic model suggests that the inclusion of NT-proBNP test at Emergency Department in base case scenario could save 1,301.06 BRL per patient, attributable to the reduction in the amount of echocardiography tests performed and in the average hospitalization length. Additionally, the economic model suggests a saving of 832.68 BRL and 1,873.53 BRL at the best and the worst case scenario, respectively. Also the one-way sensitivity analysis demonstrated that the results achieved are robust. CONCLUSIONS::  The current analysis indicates that the use of NT-proBNP test could improve the management of patients with acute Heart Failure at the Emergency Department which may result in improved therapeutic decisions and savings for Brazilian private healthcare system.