Objective: To describe and understand the effects of various changes to the Brazilian Healthcare System, including a new guideline to elaborate HTA studies for Medical Devices, governmental price regulations, and demographics. Method: The Heat Maps project provides information from 17 major health care systems around the world, including Brazil.  The Heat Maps capture: an overview of the healthcare system settings, reimbursement, HTA bodies and evaluation, evidence requirements, procurement process, value perception, and key trends and opportunities.  This data was gathered through a partnership between Pharmerit and Ethicon Inc. A targeted literature review was conducted to collect information regarding these topics. If gaps in the knowledge were identified after this review, interviews with local affiliates were conducted.    Results: Through our methodology and analysis, the following results were identified.  Brazil is growing and enjoys the largest economy and most attractive medical device market in Latin America growing 13.6% (CAGR) over the next decade. Health expenditure is valued at US$502 per capita. Brazil has 200 Million people in the public sector, and 51 Million of those also have private insurance.   New laws promote the development and purchasing of national products.  Both the public and private sectors are regulated by the Ministry of Health (MoH) and ANVISA for premarket regulatory approval. Pricing is negotiated through tenders and purchasing negotiation, and differ by region. At this time Medical Devices do not have price regulation, but in 2015 a working group was created by the MoH in order to evaluate and regulate medical devices’ prices.  HTA has grown rapidly leading to constrictions in adoption of new technologies and market access. New guidelines were prepared specifically for medical devices (HTA by CONITEC) in order to promote a better evaluation for medical devices.