OBJECTIVES: Female infertility is a global health problem, which affects approximately 120 million women worldwide. Infertility growing burden on patients, healthcare systems, and society as well. Our aim was to determine the epidemiological disease burden of female infertility of other origin in Hungary.

METHODS: Data were derived from the financial database of the Hungarian National Health Insurance Fund Administration (NHIFA), for the years 2010 and 2019. The database included the annual number of patients, number of cases, and prevalence of the utilization per 100,000 population according to age groups. The following health insurance treatment categories were included in our study: general practice care, home care, in-, and outpatient care, medical imaging, laboratory diagnostics as well as pharmaceuticals. Patients with female infertility of other origin were identified with the following code of the International Classification of Diseases 10th revision: N97.8.

RESULTS: The highest number of patients were found in outpatient care (2010: 3,870; 2019: 3,780), followed by laboratory diagnostics (2010: 2,426; 2019: 1,618) and pharmaceuticals (2010: 1,465, 2019:1759). Based on the number of patients related to outpatient care the prevalence among women was 75.8 in 2010, while 74.4 in 100,000 inhabitants in 2019. Age-specific prevalence was the highest within the age group of ’30-39’ (328.7 women). It was followed by the 20-29 years (123.0) in 2010. In 2019 the prevalence was remarkably decreased in the ’30-39’ (64.0) and ’40-49’ age groups (38.9). The mean age of the patients in outpatient care was 34.7 years in 2010 and 36.8 years in 2019.

CONCLUSIONS: The most significant increase in the number of patients was in general practice (2.1 times), and inpatient care (1.4 times). The mean age increased by 2.1 years in the study period, furthermore, the ’40-49’ age group became the second most affected group with infertility.