Evaluating the Gaps in Health Technology Assessment (HTA) Requirements: A Comparative Analysis of HTA Systems of Europe, Canada, and United States with Asia Pacific Region


Pruthi J, Verma A, Krishna A, Rai MK
EVERSANA, Mumbai, India

Presentation Documents

OBJECTIVE: This study aims to highlight the gaps in HTA requirements and existence of heterogeneity in HTA practices in 10 selected APAC countries in comparison to HTA practices in Europe, Canada, and U.S.

METHODS: A comparison of good practices in application of HTA for decision-making was carried out through a review of ISPOR’s comparative table of pharmacoeconomic guidelines, published- and grey-literature. A set of 15 principles prepared by the International Working Group were predefined for relative qualitative scoring and a scoring matrix was developed to benchmark the strength of HTA in each country.

RESULTS: The findings of this paper reveal that developed markets such as Europe and Canada have deployed HTA over the last three decades to inform health policy and reimbursement decision-making, but the adoption of HTA has been historically slow in Asia-Pacific. The scoring matrix manifests that most APAC countries have a formal HTA agency and are following a formal approach to implement HTA, but societal and patient perspectives need to be enforced via pertinent stakeholder engagement. While some HTA bodies of APAC region conduct independent reviews, others rely on findings from HTA reviews in other countries. Barring Australia which had already institutionalized HTA long ago, other countries like South Korea and Taiwan could be designated together as second most mature markets in terms of implementation of HTA.

CONCLUSION: In emerging markets, the adoption of HTA as more effective decision-making tool in healthcare is majorly restrained by lack of formal recognition and support from government bodies; pre-existing political, economic, and social policies; limited technical resources; and lack of real-world evidence. Co-collaboration among the developed and emerging countries via sharing good practices and expertise in a transparent manner will help to continue the maturation and adoption of HTA in Asia-Pacific.

Conference/Value in Health Info

2022-05, ISPOR 2022, Washington, DC, USA




Health Policy & Regulatory, Health Technology Assessment, Study Approaches

Topic Subcategory

Literature Review & Synthesis, Reimbursement & Access Policy, Systems & Structure


No Additional Disease & Conditions/Specialized Treatment Areas

Your browser is out-of-date

ISPOR recommends that you update your browser for more security, speed and the best experience on ispor.org. Update my browser now