Differences in Clinical Utility Between Thermocool SmartTouch® Surround Flow Catheter and Smarttouch or Surround Flow Catheter for Arial Fibrillation Ablation: A Systematic Literature Review and Meta-Analysis

Author(s)

Li J1, Li X1, Huang S1, Lin H1, Wang Y1, Huang H2, Chen W3, Huang X1
1Nanfang Hospital of Southern Medical University, Guangzhou, China, 2Changsha Normin Health Technology Ltd, Changsha, China, 3Normin Health Consulting Ltd, Mississauga, ON, Canada

OBJECTIVES: To synthesize the literature evidence comparing Thermocool SmartTouch® Surround Flow (STSF) with SmartTouch (ST) or Surround Flow (SF) radio-frequency catheters for clinical outcomes and efficiency associated with arial fibrillation (AF) ablation.

METHODS: This study searched the mainstay English and Chinese bibliographic databases from 2016 to 2022 for clinical studies directly comparing STSF with ST or SF catheters for AF ablation in adult patients. Meta-analysis with random effects model was used to synthesize the same outcomes reported by two or more studies.

RESULTS: 19 studies comparing STSF with ST catheter and 4 studies comparing STSF with SF for AF ablation were included for evidence synthesis. The pooled evidence indicated that STSF was associated with significantly shorter ablation time [weighted mean difference (WMD): -6.3 minutes, 95% confidence interval (CI) -12.4 to -0.2minutes, p=0.044], shorter fluoroscopy time (WMD: -1.6 minutes, 95% CI -2.8 to -0.3 minutes, p=0.014), and lower total irritation fluid volume (WMD: -492.7 ml, 95% CI -646.1 to -339.3 ml, p<0.001) than ST. The pooled complication profiles between STSF and ST were comparable. In addition, STSF was associated with significantly lower utilizations of Foley catheter [rate ratio (RR): 0.506, 95% CI 0.393 to 0.651, p<0.001] than ST. Relative to SF, STSF was associated with significantly shorter ablation time (WMD: -5.7 minutes, 95% CI -8.4 to -3.1 minutes, p<0.001) and lower risk of one-year arrhythmia recurrence after ablation surgery (RR: 0.503, 95% CI 0.379 to 0.667, p<0.001) than SF.

CONCLUSIONS: Using STSF for AF ablation was superior to using ST by significantly reducing ablation time, fluoroscopy time, and irritation fluid volume during ablation procedure. Compared to SF, STSF significantly reduced ablation time during AF ablation surgery and one-year risk of arrhythmia recurrence after AF ablation.

Conference/Value in Health Info

2022-11, ISPOR Europe 2022, Vienna, Austria

Value in Health, Volume 25, Issue 12S (December 2022)

Code

CO154

Topic

Clinical Outcomes, Study Approaches

Topic Subcategory

Clinical Outcomes Assessment, Comparative Effectiveness or Efficacy, Literature Review & Synthesis, Performance-based Outcomes

Disease

SDC: Cardiovascular Disorders (including MI, Stroke, Circulatory), STA: Medical Devices

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