Novel Approaches to Identify and Quantify Patient Input for Health Technology Assessment (HTA)


Discussion Leader: Richard Chapman, PhD, MS, The Innovation and Value Initiative, Alexandria, VA, USA
Discussants: Susan Dosreis, PhD, Center for Patient-Driven Values in Healthcare Evaluation, University of Maryland School of Pharmacy, Baltimore, MD, USA; Julia F. Slejko, PhD, University of Maryland, Baltimore, MD, USA; Lori Frank, PhD, RAND Corporation, Kensington, MD, USA

Presentation Documents


The purpose of this workshop is to demonstrate novel methods to systemically identify and quantify patient input to inform HTA.


Existing methods (e.g., economic models) used to inform HTA usually fail to capture a comprehensive set of clinical and economic outcomes of importance to patients or consider value elements that influence patient decision-making. There are gaps in existing methods to systematically identify and quantify patient input for use in HTA. Various promising approaches have been proposed and are being tested.

In this workshop, Dr. Chapman will first briefly discuss the importance and challenges of incorporating patient input in HTA (10 minutes). Drs. Susan dosReis and Julia Slejko will discuss their approach to incorporating patient input for a patient-driven HTA. Using the PAVE Center’s patient-informed value elements, they will illustrate with an application in major depressive disorder how to elicit and quantify patient input on value elements and how to translate this into meaningful patient-driven HTA (20 minutes). Dr. Frank will discuss a proof-of-concept study using goal attainment scaling and work with patient communities to “crowd source” patient input in rheumatoid arthritis, which can be used subsequently to inform multi-criteria decision analysis (MCDA). (10 minutes)

Insights from the workshop are applicable across all stakeholders: researchers will gain insight into available methods to incorporate patient input into methods to inform HTA; innovators and patient groups can learn about how to ensure comprehensive patient input is incorporated into the data collection process; and payers and HTA bodies can learn about specific approaches useful for integrating patient input into decision-making.

Conference/Value in Health Info

2021-11, ISPOR Europe 2021, Copenhagen, Denmark




Patient-Centered Research

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