Sicras-Mainar A1, Navarro-Artieda R2
1Real Life Data SLU, Badalona. Barcelona, B, Spain, 2Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain

OBJECTIVES: Cardiovascular disease is a leading cause of morbidity and mortality and high use of healthcare resources in developed countries. This study assessed to review the literature on the resource use and costs of acute coronary syndrome.

METHODS: A literature review was made using the Medline, EMBASE, PubMed, CINAHL and Cochrane Library databases. Clinical trials and observational studies were included. The full text of articles was reviewed. No metanalysis was possible due to wide variations in the data (2019).

RESULTS: Thirty-eight articles were included. We collected data on the clinical management of these patients, including the initial evaluation, confirmation of the diagnosis, risk assessment, selection of type of revascularization, hospital discharge and the follow up were taken into account. However, despite the existence of numerous national and international clinical practice guidelines, there are wide variations in adherence to their recommendations. The potential impact in terms of mortality and morbidity of the measures taken in the period immediately after coronary occlusion, both outside hospital and on arrival, justify the development of a comprehensive plan for the care of patients with ACS. The best cost-effective measures focus on reducing early mortality, serious complications and/or delays in the administration of reperfusion and, possibly, an increase in the use of primary angioplasty and/or coronary angiography, to name a few examples.

CONCLUSIONS: ACS is an important health problem and is one of the main priorities in the health policies of most countries due to its high health costs. Coordination between different care levels is essential. In spite of the wide variations in the quantification of the cost ACS, the most notable costs are those corresponding to the days of hospitalization (admissions and subsequent re-admissions). These data show the importance of primary prevention, and the need for more aggressive interventions in secondary prevention, as recommended by scientific societies.

Conference/Value in Health Info

2019-11, ISPOR Europe 2019, Copenhagen, Denmark




Economic Evaluation

Topic Subcategory

Budget Impact Analysis


Cardiovascular Disorders

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