Economic Evaluation of Pharmacist’s Antimicrobial Stewardship Interventions Through Integrated Electronic Health Record System in a Cardiac Care Facility

Author(s)

Sumaira Khan, .1, Amnah Jehangir, Pharm D2.
1Head of Pharmacy, Tabba Heart Institute, karachi, Pakistan, 2pharmacy, Tabba Heart Institute, Karachi, Pakistan.
OBJECTIVES: OBJECTIVES:
The primary objective of this study is to conduct an economic analysis of pharmacist interventions on antimicrobial usage within a hospital setting, utilizing advanced integrated electronic health record systems with clinical decision support features.
METHODS: METHODS:
A retrospective study was conducted in a cardiac care hospital from the inception of the antimicrobial stewardship program through the electronic health record system, i.e., May 2019 to May 2020. Pharmacist interventions were retrieved from the hospital’s electronic health record system. Cost-saving and cost-avoidance analyses were carried out for antimicrobial-related interventions. Economic analysis was performed and tabulated both in PKR and USD.
RESULTS: RESULTS:
Out of 2311 interventions, 2136 (92.4%) interventions were accepted, and 175 (7.5%) were either rejected or had no decision by the primary physician.
Interventions related to:
  • Bug-drug mismatch system alert (386, 16.7%)
  • Renal dose adjustments (806, 34.87%)
  • Unnecessary dual coverage (158, 6.8%)
  • Adverse drug reaction of antimicrobials through integrated lab alerts (290, 12.54%)
  • IV to PO switch (496, 21.46%)
  • Duration of therapy (175, 7.5%)
Review of antibiotics is recorded as 100%, as all antibiotic orders appeared in the clinical pharmacist’s daily queue for review and acceptance. The acceptance rate is recorded as 92.4% by the primary physician. Overall, cost analysis showed that pharmacist interventions through the electronic health record system saved around 150,110.23 US dollars.
CONCLUSIONS: CONCLUSIONS:
Antimicrobial stewardship services provided by clinical pharmacists through an integrated electronic health record system are a cost-saving program. The cost saved per intervention for this study is around USD 65.

Conference/Value in Health Info

2025-09, ISPOR Real-World Evidence Summit 2025, Tokyo, Japan

Value in Health Regional, Volume 49S (September 2025)

Code

RWD183

Topic Subcategory

Data Protection, Integrity, & Quality Assurance

Disease

SDC: Cardiovascular Disorders (including MI, Stroke, Circulatory)

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