Geographic Disparities in Chronic Kidney Disease Hospitalizations: Exploring Associations with Neighborhood Socioeconomic Status in Texas

Author(s)

Zhong L1, Farej R2, Andreyeva E1, Farag Y2, Singh R2, Kong SX2, Sorescu A1, Ma P1, Du Y2, Udeani G1, Guerrero G2, Ohsfeldt RL1, Young J3, Cameron J2, Williamson T2
1Texas A&M University, College Station, TX, USA, 2Bayer U.S. LLC, Whippany, NJ, USA, 3Vault Bioventures, San Diego, CA, USA

OBJECTIVES:

Individuals with chronic kidney disease (CKD) are more likely to be hospitalized, yet the impact of neighborhood Socioeconomic Status (SES) on hospitalizations among those with CKD remains poorly understood. This study aims to evaluate the geographic variation of hospitalizations with a CKD diagnosis in Texas and identify the associations with county-level SES.

METHODS:

A cross-sectional analysis was conducted using 2021 Texas Inpatient Public Use Data, which includes statewide discharge information from Texas hospitals. Hospitalizations with a CKD diagnosis (CKD-Hosp) were identified. Heatmaps were created for the number of CKD-Hosp by county and for CKD-Hosp rates and normalized by the county population. Hospital discharge data were supplemented with county-level SES index constructed using data from the American Community Survey. Ordinary least square (OLS) regression models were estimated to identify the associations between county-level SES and CKD-Hosp rates.

RESULTS:

In 2021, there were 2,455,233 hospitalizations among Texas residents aged 18 years and above, of which 441,466 (18.0%) had a CKD diagnosis (CKD-Hosp). The number of CKD-Hosp is strongly correlated with county population, with high concentrations within or near metropolitan/urban areas. After adjusting for county population, the average CKD-Hosp rate in 254 Texas counties was 1,687±604 per 100,000 people. Disparities in income, property values, poverty, unemployment, and education were associated with statistically significant differences in CKD-Hosp rates. The top 25% of counties with highest SES index scores have on average 422 fewer CKD-Hosps per 100,000 people compared with the bottom 25% of counties (P<0.001).

CONCLUSIONS:

The study reveals substantial disparities in CKD-Hosp rates across Texas counties. Counties with higher SES exhibit notably fewer CKD-Hosps per 100,000 people compared to lower SES counties with the understood limitation of residual confounding. These findings underscore the critical need to address socioeconomic disparities as a potential avenue for mitigating the burden of hospitalizations among CKD patients.

Conference/Value in Health Info

2024-05, ISPOR 2024, Atlanta, GA, USA

Value in Health, Volume 27, Issue 6, S1 (June 2024)

Code

EPH125

Topic

Economic Evaluation, Epidemiology & Public Health, Health Policy & Regulatory

Topic Subcategory

Health Disparities & Equity, Public Health

Disease

No Additional Disease & Conditions/Specialized Treatment Areas, Urinary/Kidney Disorders

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