Objective

The task force will develop good practice recommendations for the application of Generative AI for HEOR SLRs and a comprehensive reporting checklist.

Rationale

The development of good practice guidance on the use of Gen AI in SLRs is critically important to the HEOR community, as the rapid integration of AI into healthcare research presents both opportunities and challenges. Gen AI tools, such as large language models (LLMs), have demonstrated the potential to augment various stages of evidence synthesis, including search strategy development, data extraction, and report generation. However, these tools also introduce significant complexity, including the risk of generating fabricated content, inaccuracies, and inconsistent results, all of which could undermine the credibility of research outcomes.

Establishing an ISPOR Good Practices Task Force in this area will provide the HEOR community with critical guidance on how to responsibly integrate Gen AI into evidence generation. It will ensure that researchers and practitioners can leverage these powerful tools while maintaining the rigorous standards of research integrity that the field demands.

Co-Chairs:

Jag Chhatwal, PhD

Associate Professor and Director of the Institute for Technology Assessment, Harvard Medical School / Massachusetts General Hospital
Boston, MA, United States

Rachael Fleurence, PhD

Head of Evidence and AI Solutions, Value Analytics Labs
Boston, MA, United States

Leadership Group

Rakesh Aggarwal

Professor of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences
Lucknow, UP, India

Turgay Ayer

Chief Technology Officer, Value Analytics Labs
Boston, MA, United States

Ran Balicer, PhD, MD

Chief Innovation Officer, Clalit Health Services
Tel Aviv, Israel

Jiang Bian

Professor and Chief Data Scientist, University of Florida
Gainesville, FL, United States

Saskia Cheyne

Research Fellow, Monash University
Sydney, NSW, Australia

Dalia Dawoud, MSc, PhD, BSc

Director and CEO, PEHTA Consulting LTD
London, LON, United Kingdom

Diana Delnoij

Chief Scientific Officer, Zorginstituut Nederland (ZIN)
Diemen, Netherlands

Ruth Faden

Johns Hopkins University
Baltimore, MD, United States

Sven Klijn, MSc, BSc

Director, Bristol Myers Squibb
Utrecht, UT, Netherlands

Riaz Qureshi

Epidemiologist and Assistant Professor, Department of Ophthalmology, School of Medicine, Department of Epidemiology, School of Public Health, University of Colorado Anschutz Medical Campus, School of Public Health
Denver, CO, United States

Rebecca Trowman

HTAi Global Policy Forum Scientific Secretary, Health Technology Assessment international (HTAi)
Perth, WA, Australia
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