Trends in Epidemiology and Mortality of Patients With Prostate Cancer in Germany: A Retrospective Study Using German Claims Data
Author(s)
Müller S1, Dornig S2, Wilke T3, Mevius A3
1GIPAM GmbH, Wismar, MV, Germany, 2AOK PLUS, Jena, Germany, 3Institut für Pharmakoökonomie und Arzneimittellogistik e.V. (IPAM), Wismar, Germany
OBJECTIVES: Despite progress in the early detection and treatment of prostate cancer (PRC), it remains a common cancer diagnosis in men, associated with a substantial mortality in late disease stages. This research aims to estimate the incidence/prevalence of PRC in Germany and to describe trends in mortality in the last ten years.
METHODS: Utilizing claims data from AOK PLUS (German sickness fund with 3.5 million insured persons), PRC cases were identified by outpatient and inpatient diagnoses (ICD-10-GM: C61). Cumulative PRC incidence in 2012/2016/2022 and point prevalence on January 1st of the following year were assessed and extrapolated (age-standardized) to the overall German male population. Standardized mortality rates for 2012/2016/2022 were evaluated in cross-sectional PRC samples.
RESULTS: Age-standardized German PRC incidence and prevalence (in males) in 2012/2016/2022 were 0.191%/0.181%/0.217% and 1.449%/1.548%/1.762%, respectively. Based on a German male population of 41 million men, this translates into 88,970 incident PRC cases in the year 2022 and 722,420 PRC-prevalent patients on January 1, 2023. Yearly mortality in the extrapolated prevalent GER male PRC population were 6.4% in 2012, 6.2% in 2016, and 6.8% in 2022.
CONCLUSIONS: PRC incidence and prevalence estimates based on claims data are much higher than in the official German RKI (Robert Koch Institute) statistics, probably due to a certain degree of overreporting in claims data, but mainly due to missed cases in the cancer registries resulting from underreporting in outpatient and inpatient practices Reports from inpatient and outpatient oncology sites form the basis of the RKI statistics. Mortality in PRC-prevalent increased slightly in the last ten years, indicating the increasing health burden resulting from PRC.
Conference/Value in Health Info
Value in Health, Volume 27, Issue 12, S2 (December 2024)
Code
EPH47
Topic
Epidemiology & Public Health
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, Oncology