OBJECTIVES: Despite the worldwide trend of increasing utilization of generics, Greece falls behind in achieving optimal penetration of generics. Misperceptions surrounding generic drugs can have a significant impact on their overall uptake. The objective of this study was to evaluate the perceptions of Greek patients regarding generic medicines.

METHODS: A cross-sectional study was conducted in Greece within an outpatient setting from April 2022 to July 2022. To gather data, a self-administered anonymous questionnaire was utilized. The questionnaire was developed based on previous studies with similar objectives.

RESULTS: Among the 351 respondents, 83.9% claimed adequate knowledge about generics. Their main information courses were the internet (30.3%), media (30%), pharmacists (21.6%), and family doctors (19.6%). The majority of patients (78%) perceived generic drugs as effective and safe, 67% to be similar in quality, and 81% as cheaper compared to brand-name drugs. However, only 74% believed they contain the same active substances. Approximately 42% expressed more trust in brand-name products than generics, and only 63% reported a positive view of generics. Furthermore, 11% stated that generics do not provide any benefit to the society, and 24% expressed concerns if their doctor switched from a brand-name product to a generic.

CONCLUSIONS: Despite a significant percentage of patients claiming to have sufficient knowledge about generics, a notable proportion of respondents still hold negative perceptions of generic drugs. The findings highlight the need for patient education to correct misperceptions and improve attitudes towards generic drugs, ultimately increasing their acceptance and utilization among Greek patients.