Treatment Patterns and Healthcare Resource Utilization in Patients Diagnosed With CRSwNP in HMO From Colombia: A Real Word Evidence Study
Author(s)
Carlos Bello, Msc1, Luz E. Perez Jaramillo, M.D. M.Sc2, Jhon E. Bolaños, MSc, MD1, Farley Gonzalez, MD, MSc3;
1IPS Suramericana Cali, Cali, Colombia, 2IPS Suramericana, Medellin, Colombia, 3IPS Suramericana Medellin, Medellin, Colombia
1IPS Suramericana Cali, Cali, Colombia, 2IPS Suramericana, Medellin, Colombia, 3IPS Suramericana Medellin, Medellin, Colombia
Presentation Documents
OBJECTIVES: To describe the treatment patterns and healthcare attention of patients diagnosed with chronic rhinosinusitis with nasal polyps (CRSwNP) between 2013 to 2021 in one Health Management Organization (HMO) in Colombia.
METHODS: This was a non-interventional, retrospective, descriptive study. Patients over 18 years of age with record of any of the International Classification of Diseases codes (ICD-10) J31, J32, J33, J34 and diagnostic confirmation of nasal polyps issued by otorhinolaryngologist or allergist between January 2013 and December 2021 were included. First registered ICD-10 code was defined as index date. Follow-up limit was established until December 2023. Medical records and administrative databases from the HMO were used to determine the clinical characteristics and healthcare services. The frequency of use of each resource was calculated as the number of services per patient/year.
RESULTS: 6,300 patients were included (mean age: 42.87 years, 51.92% women). Mean follow-up time was 78.02 months (SD: 28.29). Initial diagnosis was mainly made by otorhinolaryngologists (63.68%) and general practitioners (31.16%). The most common pharmacotherapy was intranasal beclomethasone (71.86%) and loratadine (70.26%). 46.58% had intranasal corticosteroids for more than 1 year and 77.45% used oral corticosteroids for up to 6 months. Low prescription of biologics was observed, mainly using dupilumab (1.77%). 24.03% of subjects underwent surgery and 1.62% had 2 or more interventions. Median of the time from the index date to first surgery was 21.7 months estimated by Kaplan-Meier. The most common surgery type was transnasal endoscopic incision of paranasal sinuses (58.59%). The most frequent utilization of healthcare resources were medicines supply and specialized medical consultation, with annual mean of 6.31 (SD: 7.68) and 1.65 (SD: 1.68) services per patient, respectively.
CONCLUSIONS: Most CRSwNP patients were diagnosed and managed by specialist with a low frequency of visits. Corticosteroids, antihistamines and surgery were the main treatments choices while biologics use is still limited.
METHODS: This was a non-interventional, retrospective, descriptive study. Patients over 18 years of age with record of any of the International Classification of Diseases codes (ICD-10) J31, J32, J33, J34 and diagnostic confirmation of nasal polyps issued by otorhinolaryngologist or allergist between January 2013 and December 2021 were included. First registered ICD-10 code was defined as index date. Follow-up limit was established until December 2023. Medical records and administrative databases from the HMO were used to determine the clinical characteristics and healthcare services. The frequency of use of each resource was calculated as the number of services per patient/year.
RESULTS: 6,300 patients were included (mean age: 42.87 years, 51.92% women). Mean follow-up time was 78.02 months (SD: 28.29). Initial diagnosis was mainly made by otorhinolaryngologists (63.68%) and general practitioners (31.16%). The most common pharmacotherapy was intranasal beclomethasone (71.86%) and loratadine (70.26%). 46.58% had intranasal corticosteroids for more than 1 year and 77.45% used oral corticosteroids for up to 6 months. Low prescription of biologics was observed, mainly using dupilumab (1.77%). 24.03% of subjects underwent surgery and 1.62% had 2 or more interventions. Median of the time from the index date to first surgery was 21.7 months estimated by Kaplan-Meier. The most common surgery type was transnasal endoscopic incision of paranasal sinuses (58.59%). The most frequent utilization of healthcare resources were medicines supply and specialized medical consultation, with annual mean of 6.31 (SD: 7.68) and 1.65 (SD: 1.68) services per patient, respectively.
CONCLUSIONS: Most CRSwNP patients were diagnosed and managed by specialist with a low frequency of visits. Corticosteroids, antihistamines and surgery were the main treatments choices while biologics use is still limited.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
RWD18
Topic
Real World Data & Information Systems
Topic Subcategory
Health & Insurance Records Systems
Disease
SDC: Respiratory-Related Disorders (Allergy, Asthma, Smoking, Other Respiratory)