Machine Assisted Rapid Scoping Review: Current Therapeutic Trends for Tinnitus Cure and Control
Author(s)
Khambholja K1, Patel D2, Chhaya V3
1Genpro Research Inc, Waltham, MA, USA, 2Genpro Research, Vadodara, GJ, India, 3Genpro Research Pvt. Ltd., Vadodara, GJ, India
Presentation Documents
OBJECTIVES:
To assess the latest knowledge in the field of tinnitus management and inform the clinical fraternity with evidence-based knowledge.METHODS:
A literature search was performed on PubMed, Cochrane, and Google using an AI-powered evidence synthesis tool – MaiA. We retrieved randomized and non-randomized controlled trials, systematic reviews, meta-analyses, and observational studies from 2014 to 2021(search date 1 Apr 2021) on chronic tinnitus patients within the context of evidence-based guidelines available on tinnitus therapies. . We excluded studies on epidemiology, technical objectives assessing other than efficacy/safety outcomes, or review articles. Charted data from selected sources of evidence (related to study characteristics, intervention, sample size, efficacy and safety data, and quality of life-related outcomes as applicable) were summarized.RESULTS: We retrieved five evidence-based clinical practice guidelines (US, EU, and Japan regions). Of total 506 results, 205 underwent machine assisted rapid screening based on eligibility criteria and 38 were included for the final charting. Three major treatment trends emerged: 1. Medical technology (stimulation, sound, neurofeedback); 2. Behavioural/habituation (retraining, cognitive behavioural therapies [CBT]); and 3. Pharmacological, herbal/complementary and alternative medicine (acupuncture, antioxidants, ginkgo biloba, other investigational drugs). Digital interventions were demonstrated by two studies showing therapeutic potential of internet-based CBT when guided by audiologist. However, none of these were recommended to practice as per the latest EU guideline in 2019 due to limited strength of evidence, except for CBT.
CONCLUSIONS:
Machine assisted rapid scoping review can help in fast and robust evidence synthesis. Although tinnitus guidelines did not recommend stimulation therapies, tinnitus research is seen focusing on stimulation. Therefore, it is highly recommended that clinicians consider clinical practice guidelines when making treatment recommendations and make distinction between established management approaches with good evidence and emerging treatment approaches for tinnitus management.Conference/Value in Health Info
Value in Health, Volume 26, Issue 6, S2 (June 2023)
Code
EPH88
Topic
Study Approaches
Topic Subcategory
Literature Review & Synthesis
Disease
No Additional Disease & Conditions/Specialized Treatment Areas