OBJECTIVES: Most countries in Emerging Markets follow guidance from the FDA and EMA for RWE generation and use. In these countries, there is demand amongst healthcare stakeholders to grow regional RWE capabilities to support clinician, payer, and regulator decision-making in oncology. This presentation aims to provide: perspectives on the current oncology RWE landscape in these countries; identification and prioritization of high-impact RWE opportunities; and, considerations for implementing the highest-priority opportunity.

METHODS: The RWE Insights Committee in Oncology (RICO) for Emerging Markets was established to inform on high-impact RWE opportunities from 15 oncologist KOLs and 9 payer advisors, across 16 countries in Latin America, Africa and the Middle East, and Asia Pacific. Two sets of primary market research-based, panel-style workshops were conducted: first, to characterize the oncology RWE landscape and identify future opportunities for investment; second, to prioritize opportunities and ideate on implementation design.

RESULTS: When characterizing the oncology RWE landscape, panelists indicated: greatest familiarity with traditional study designs (cohort, cross-sectional), most frequently used real-world data sources (EMR, medical charts), and common RWE uses (understanding treatment options, guiding future research). Of the RWE opportunities, local population studies, value-based contracting, and a technology-enabled RWE platform were prioritized as most impactful. The platform envisioned would include a stable, cross-regional network of data sources (usually hospitals) for a defined tumor type (e.g., breast, lung) that offers on-demand, clinically-rich data for a sufficiently large patient sample.

CONCLUSIONS: Despite lacking widespread infrastructure, Emerging Market oncologists and payers have deep RWE expertise. Among them, likeminded stakeholders are eager to collaborate on designing and implementing RWE opportunities, like the technology-enabled RWE platform. Such opportunities would advance regional RWE capabilities, and further enable RWE use in local decision-making.