Clinical Effectiveness of Pacemaker in High-Risk Patients with Cardiovascular Diseases: A Systematic Review and Metanalysis
Author(s)
Seshu P1, Kachroo K2, Sharma J3, Rm K4, Varalakshmi G5
1Kalam Institute of Health Technology, Visakhapatnam, AP, India, 2Kalam Institute of Health Technology, Visakhapatnam, India, 3Andhra Pradesh MedTech Zone, Andhra Pradesh, India, 4Kalam Institute of Health Technology, AMTZ- A JBI Affiliated group, Visakhapatnam, India, 5Andhra Pradesh Medical Technology Zone (AMTZ), Vishakhapatnam, AP, India
Presentation Documents
OBJECTIVES:
A cardiac pacemaker (PM) is a medical device that uses electrical impulses delivered by electrodes to contract the heart muscle and regulate the heart rate. The main purpose of this device is to maintain a proper heart rate. Pacemakers are essential not only for the treatment of arrhythmias and heart failure, but also for the treatment of cardiovascular diseases. Therefore, this review hypothesizes that cardiovascular disease patients receiving treatment 'with or without pacemaker may increase or decrease the risk of mortality. The objectives of this study were to analyse the pacemaker evidence to conduct a systematic review to determine the clinical efficacy of pacemaker implantation in high-risk patients requiring surgery with outcomes with reduced of risk mortality.METHODS:
A comprehensive search was performed at various electronic databases using PubMed, Web of Science, Google Scholar and Cochrane. A PRISMA method is used to curate and collocate the studies. Quantitative data were pooled into statistical meta-analyses using the Cochrane Review Manager (RevMan) to compare clinical efficacy with and without pacemakersRESULTS:
A total of 3334 articles were obtained and after evaluation, 10 articles were accepted that answered the research questions and met the criteria for systematic review and meta-analysis. Therefore, the metanalysis found that the risk of mortality was increased in patients treated without a pacemaker and decreased mortality in those patients treated with a pacemaker showing (risk ratio 1.23, (1.15 to 1.32) with a 95% confidence interval.CONCLUSIONS:
In this review we found that pacemakers played an important role in patients’ recovery and reduced risk of Mortality. This adds to the confidence that pacemakers will become more prevalent in the next few years.Conference/Value in Health Info
Value in Health, Volume 26, Issue 6, S2 (June 2023)
Code
CO7
Topic
Clinical Outcomes, Medical Technologies, Study Approaches
Topic Subcategory
Comparative Effectiveness or Efficacy, Literature Review & Synthesis, Medical Devices
Disease
Cardiovascular Disorders (including MI, Stroke, Circulatory), Medical Devices