Exploring Health-Related Quality of Life, Renal Dysfunction, and Bladder Stone Risks in Individuals With Spinal Cord Injury Using Different Bladder Emptying Methods: Findings from Two National Surveys in China
Author(s)
Fan Zhang, MSc1, Chengaxin Duan, MSc1, Runmin Liu, MBA2, Xiao Wen Luah, MSc3, Sijie Han, MSc2, Lu Tian, BSc4.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
Presentation Documents
OBJECTIVES: This study explores the HRQoL and the odds ratios (ORs) of bladder stones and renal dysfunction among community-dwelling Chinese individuals with spinal cord injury (SCI) with various bladder emptying methods.
METHODS: Two nationwide surveys were conducted across China in 2020 (n=2,983) and 2023 (n=3,027). Respondents were categorized according to the respective bladder management methods: normal voiding, intermittent catheterization (IC), transurethral indwelling catheterization (TIC),suprapubic indwelling catheterization (SIC), others (e.g. pads, bladder expression) and mixed methods. HRQoL was assessed using SF-36 and reported through Physical Health Composite (PHC) and Mental Health Composite (MHC)Scores. The ORs of renal dysfunction and bladder stones are calculated using 2x2 tables, comparing the frequency of reported complications such as bladder stones and renal dysfunction across bladder management techniques.
RESULTS: Survey respondents were predominantly male (aged45-46), paraplegic, with thoracic injuries, requiring caregivers and wheelchairs. Respondents with normal voiding reported higher PHC and MHC scores than respondents on IC, TIC, SIC, others and mix methods (p<0.05). In 2020, IC users reported higher PHC than TIC and SIC users (p<0.05), a similar but non-significant trend was also observed in 2023. Respondents on TIC had higher odds of bladder stones and renal dysfunction compared to those on IC, with significance observed only in 2020 data. Respondents on SIC showed significantly higher odds of bladder stones and renal dysfunction compared to those on IC in both years.
CONCLUSIONS: Respondents using IC reported higher PHC scores compared to those on TIC and SIC. Respondents on IC reported lower odds for bladder stone and renal dysfunction compared to respondents on TIC and SIC. These findings underscore the need for patient-centered bladder management strategies to optimize HRQoL and reduce the odds of complications such as bladder stone and renal dysfunction.
METHODS: Two nationwide surveys were conducted across China in 2020 (n=2,983) and 2023 (n=3,027). Respondents were categorized according to the respective bladder management methods: normal voiding, intermittent catheterization (IC), transurethral indwelling catheterization (TIC),suprapubic indwelling catheterization (SIC), others (e.g. pads, bladder expression) and mixed methods. HRQoL was assessed using SF-36 and reported through Physical Health Composite (PHC) and Mental Health Composite (MHC)Scores. The ORs of renal dysfunction and bladder stones are calculated using 2x2 tables, comparing the frequency of reported complications such as bladder stones and renal dysfunction across bladder management techniques.
RESULTS: Survey respondents were predominantly male (aged45-46), paraplegic, with thoracic injuries, requiring caregivers and wheelchairs. Respondents with normal voiding reported higher PHC and MHC scores than respondents on IC, TIC, SIC, others and mix methods (p<0.05). In 2020, IC users reported higher PHC than TIC and SIC users (p<0.05), a similar but non-significant trend was also observed in 2023. Respondents on TIC had higher odds of bladder stones and renal dysfunction compared to those on IC, with significance observed only in 2020 data. Respondents on SIC showed significantly higher odds of bladder stones and renal dysfunction compared to those on IC in both years.
CONCLUSIONS: Respondents using IC reported higher PHC scores compared to those on TIC and SIC. Respondents on IC reported lower odds for bladder stone and renal dysfunction compared to respondents on TIC and SIC. These findings underscore the need for patient-centered bladder management strategies to optimize HRQoL and reduce the odds of complications such as bladder stone and renal dysfunction.
Conference/Value in Health Info
2025-09, ISPOR Real-World Evidence Summit 2025, Tokyo, Japan
Value in Health Regional, Volume 49S (September 2025)
Code
RWD236
Topic Subcategory
Health & Insurance Records Systems
Disease
SDC: Injury & Trauma