Understanding Awareness Obstacles and Facilitators of Generic Medication Substitution Among Healthcare Professionals in Pakistan: A Qualitative Study

Author(s)

Ayesha Azam, MPhil1, MUHAMMAD AMIR HAMZA, MPhil1, Bushra Batool Zahra, MPhil1, Rehana Sarwat, MPhil1, Shanzah Anjum, Post-RN BSN2, Uzair Aslam, MBBS, MD3, Ali Ahmed, MPhil, PharmD, PhD4.
1Riphah International University, Islamabad, Pakistan, 2Nursing, Advance International Hospital, Islamabad, Pakistan, 3Kuslum International Hospital, Islamabad, Pakistan, 4University of California San Diego, San Diego, CA, USA.
OBJECTIVES: The global utilization of generic medications has progressively increased due to financial constraints on pharmaceutical budgets. The insufficient knowledge among healthcare professionals regarding generics results in reservations towards their use, especially regarding their efficacy, which poses a significant obstacle to the wider use of these medications. Evaluating healthcare providers' attitudes and comprehension of generic drugs may identify potential obstacles to increased utilization of these medications. Therefore, we aim to evaluate the knowledge, perceptions, barriers, and enablers related to generic substitution in Pakistan.
METHODS: Semi-structured interviews were conducted with 15 physicians, 15 pharmacists, and 10 nurses from March 2024 to August 2024 at Kulsum International Hospital (KIH), Advance International Hospital (AIH), and Fauji Foundation Hospital (FFH) in the twin cities of Islamabad and Rawalpindi, Pakistan. The audio recordings of the interviews were initially transcribed in Urdu, subsequently translated into English, and thematically analyzed using a phenomenological approach.
RESULTS: The present investigation indicates that generic medications are typically freely available and easily accessible. Generic medications are considered more economical and can enhance rational prescribing practices. However, some respondents raise concerns regarding the efficacy and safety of these drugs. Numerous health care practitioners have highlighted the necessity for clear and standardized rules about generic substitution.
CONCLUSIONS: Substantial gaps were recognized in the understanding and opinions of healthcare providers concerning generic medications, particularly regarding their efficacy and safety. Various training programs should be implemented to enhance knowledge about generic drugs among healthcare professionals and patients.

Conference/Value in Health Info

2025-11, ISPOR Europe 2025, Glasgow, Scotland

Value in Health, Volume 28, Issue S2

Code

HSD120

Topic

Clinical Outcomes, Economic Evaluation, Health Service Delivery & Process of Care

Disease

Generics, No Additional Disease & Conditions/Specialized Treatment Areas

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