Presentation (CTI)

OBJECTIVES: Prostate cancer is the second most diagnosed cancer, and the fifth leading cause of cancer related deaths among men worldwide. This study analyzed SEER data from 2000 to 2022 to evaluate trends in incidence, prevalence, and survival, including subgroup analyses by age, race, and disease stage to identify underlying patterns and disparities
METHODS: Incidence, prevalence and survival data were extracted using SEER*Stat software. Age-adjusted incidence rates were analyzed in 10-year and 5-year intervals. Descriptive trend analyses were used to identify patterns and forecast future trajectories.
RESULTS: The highest incidence of prostate cancer occurred among men aged 70-79, followed by the 60-69 and 80-89 age groups. A more detailed 5-year analysis showed a peak incidence among those aged 70-74, while the highest prevalence was in the 65-69 age group. Prevalence among individuals under 50 was extremely low (<0.02%). Most cases were diagnosed at a localized stage (prevalence = 0.49%), followed by regional and distant stages. Racial disparities were pronounced: Black men had the highest prevalence (1.01%), followed by White (0.69%), Asian (0.32%), and American Indian (0.23%). Regarding survival, Asian and White patients had better outcomes than Black and American Indian patients. Patients diagnosed with distant-stage disease had poorer survival compared to those diagnosed at localized or regional stages, emphasizing the importance of early detection.
CONCLUSIONS: Prostate cancer burden varies significantly by age, race, and stage. Prevalence peaks at ages 65-69, indicating a need for enhanced screening in this age group. While persistent racial disparities in outcomes clearly point to the need for equitable access to care, differences in incidence may reflect a combination of access, environmental exposures, and other race-associated risk factors that merit further study. Tailored public health strategies are essential to improve survival among high-risk and underserved populations.