Delphi Panel for Standardizing Outcome Measures in Radical Prostatectomy Surgical Care Pathway
Author(s)
Anderson FERNANDES Santos, MSc1, Alessandro Gonçalves Campolina, MD, PhD2, Gilberto Rodrigues, MD3, Guilherme da Costa Souza, MSc1, Nathalia Celini, MSc4, Ulysses Ribeiro Jr., MD, PhD3.
1Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil, 2Cancer Institute of Sao Paulo - ICESP, Sao Paulo, Brazil, 3Cancer Institute of Sao Paulo - ICESP, São Paulo, Brazil, 4Strattner, São Paulo, Brazil.
1Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil, 2Cancer Institute of Sao Paulo - ICESP, Sao Paulo, Brazil, 3Cancer Institute of Sao Paulo - ICESP, São Paulo, Brazil, 4Strattner, São Paulo, Brazil.
OBJECTIVES: Minimally invasive surgery (MIS), particularly robot-assisted surgery (RAS), represents a major advancement in surgical practice. However, evaluating the clinical and economic impact of such technologies poses significant challenges, especially due to the need to prioritize functional outcomes, recovery, and quality of life factors often not captured by traditional randomized controlled trials and are central to assessing value beyond traditional metrics. To develop a core outcome set for clinical data collection in patients undergoing radical prostatectomy, using a modified Delphi method.
METHODS: A modified Delphi study was conducted with healthcare professionals, researchers, and representatives from patient organizations. A total of 46 panelists were invited. An initial list of 27 outcomes across three domains was identified through a literature review. Two rounds of online Delphi surveys were used to refine the list, with participants rating each outcome on a nine-point Likert scale.
RESULTS: In the first round, 20 out of 46 invited experts (43%) responded. Consensus was reached on all 27 proposed items, and four additional outcomes were suggested by the panel. In the second round, 16 experts (35%) responded and consensus was reached on all items, resulting in a final framework of 31 outcomes.
CONCLUSIONS: This study developed the first core outcome set framework in Brazil for patients undergoing radical prostatectomy, based on national expert consensus through the Delphi method. The framework reflects clinical, patient-centered, and health system-relevant priorities.
METHODS: A modified Delphi study was conducted with healthcare professionals, researchers, and representatives from patient organizations. A total of 46 panelists were invited. An initial list of 27 outcomes across three domains was identified through a literature review. Two rounds of online Delphi surveys were used to refine the list, with participants rating each outcome on a nine-point Likert scale.
RESULTS: In the first round, 20 out of 46 invited experts (43%) responded. Consensus was reached on all 27 proposed items, and four additional outcomes were suggested by the panel. In the second round, 16 experts (35%) responded and consensus was reached on all items, resulting in a final framework of 31 outcomes.
CONCLUSIONS: This study developed the first core outcome set framework in Brazil for patients undergoing radical prostatectomy, based on national expert consensus through the Delphi method. The framework reflects clinical, patient-centered, and health system-relevant priorities.
Conference/Value in Health Info
2025-11, ISPOR Europe 2025, Glasgow, Scotland
Value in Health, Volume 28, Issue S2
Code
CO69
Topic
Clinical Outcomes
Topic Subcategory
Clinical Outcomes Assessment, Performance-based Outcomes
Disease
Oncology, Reproductive & Sexual Health, Surgery