Presentation (CTI)

OBJECTIVES: The Asia-Pacific(APAC) region is an emerging hub for Real-World-Evidence(RWE), leveraging diverse, often underrepresented populations in clinical trials, with expanding healthcare systems, and increasing access to claims, EHRs, registries, and biobanks. Emerging markets are started realizing the value of investing in robust RWD to inform health policy, research, and innovation. However, identifying fit-for-purpose and accessible databases remains a significant challenge across APAC. This study seeks to evaluate the spectrum of RWD sources available in APAC, aiming to identify databases striking a balance between accessibility and content richness.
METHODS: A narrative review of RWE publications from Jan2021-May2025 was conducted and classified the databases by type, data attributes, and the nature of the evidence presented. A quadrant analysis was performed to evaluate databases based on content richness and ease of access, with the top-right quadrant denoting those with high accessibility, and the bottom-left identifying databases with robust content but restricted availability.
RESULTS: The APAC region hosts several interesting databases to support HEOR. South Korea’s NHID and HIRA, and Taiwan’s NHIRD, offer population-wide data on healthcare use, diagnoses, and mortality. Japan contributes through MDV, JMDC, DeSC, and Biobank Japan, which provide extensive claims and clinical information. Singapore’s NEHR and NRDO support research and policy, but access is limited for non-academics. Malaysia’s NHMS, MyHDW, and disease registries and Thailand’s NHSO and MOPH datasets are instrumental in regulatory decision-making and outcomes-research. China’s UEBMI and CHIRA enable analyses of cost sensitivity and real-world evidence generation. India’s AB-PMJAY claims data and structured EHRs from major hospitals are increasingly used in HEOR. Despite decisive, the region still grapples with the common issues of fragmentation, accessibility, and privacy constraints.
CONCLUSIONS: APAC's diverse and growing RWD present unique opportunities to generate focused insights on local populations. With improving data governance and access, the region is set to play a key role for global research.