Comparison EQ-5D-Y-3L Responses Between Child Self-Reports and Caregiver Proxy Reports
Author(s)
Eliza Lai-Yi Wong, PhD1, Annie Wai-ling Cheung, MPhil1, Judy Sze, BSc1, Amy Yuen-Kwan Wong, MSc1, Richard Xu, PhD2, Clement Cheuk Wai Ng, PhD1.
1The Chinese University of Hong Kong, Hong Kong, China, 2Hong Kong Polytechnic University, Hong Kong, China.
1The Chinese University of Hong Kong, Hong Kong, China, 2Hong Kong Polytechnic University, Hong Kong, China.
OBJECTIVES: Although proxy reports of health status show high reliability and acceptable agreement with child self-reports, further research is needed to refine individual dimensions for younger populations, particularly given cultural and healthcare system differences across regions. To support accurate HRQoL assessment in the local context, this study aimed to evaluate differences between the EQ-5D-Y-3L self-report and proxy-report versions among children and caregivers in Hong Kong.
METHODS: The study aimed to recruit 600 children aged 8-17 and their parents or primary caregiver who were defined as those responsible for the child’s basic daily needs as proxy respondents. A cross-sectional, face-to-face survey using a self-administered electronic questionnaire has been conducted since Jun 2025. Both children and their proxies assessed the child’s health-related quality of life (HRQoL) using the EQ-5D-Y-3L and the PedsQL Generic at two consecutive time points. The proxy versions of the EQ-5D-Y-3L will be evaluated for feasibility, distributional properties, convergent validity, test-retest reliability, and responsiveness. Findings presented in this abstract are based on baseline data of the first 34 respondents, focusing on the agreement between each self-report version and its corresponding proxy.
RESULTS: A higher proportion of children (70.6%) reported full health compared to their proxies (55.9%). Discrepancies between self- and proxy-reports were greatest in the dimensions of pain/discomfort (32.4%) and emotional well-being (feeling worried, sad or unhappy) (35.3%). However, differences were relatively minor in mobility (8.8%), self-care (5.9%), and usual activities (5.9%). Despite these dimensional differences, the mean Visual Analogue Scale (VAS) scores were comparable between self-reports (80.7) and proxy-reports (80.9).
CONCLUSIONS: The similarity in VAS scores indicates a general alignment in overall health perception between self- and proxy-reports. The local application of monitoring health change of healthcare interventions or technologies among children could be enriched if the EQ-5D-Y proxy version is confirmed its validity in the application.
METHODS: The study aimed to recruit 600 children aged 8-17 and their parents or primary caregiver who were defined as those responsible for the child’s basic daily needs as proxy respondents. A cross-sectional, face-to-face survey using a self-administered electronic questionnaire has been conducted since Jun 2025. Both children and their proxies assessed the child’s health-related quality of life (HRQoL) using the EQ-5D-Y-3L and the PedsQL Generic at two consecutive time points. The proxy versions of the EQ-5D-Y-3L will be evaluated for feasibility, distributional properties, convergent validity, test-retest reliability, and responsiveness. Findings presented in this abstract are based on baseline data of the first 34 respondents, focusing on the agreement between each self-report version and its corresponding proxy.
RESULTS: A higher proportion of children (70.6%) reported full health compared to their proxies (55.9%). Discrepancies between self- and proxy-reports were greatest in the dimensions of pain/discomfort (32.4%) and emotional well-being (feeling worried, sad or unhappy) (35.3%). However, differences were relatively minor in mobility (8.8%), self-care (5.9%), and usual activities (5.9%). Despite these dimensional differences, the mean Visual Analogue Scale (VAS) scores were comparable between self-reports (80.7) and proxy-reports (80.9).
CONCLUSIONS: The similarity in VAS scores indicates a general alignment in overall health perception between self- and proxy-reports. The local application of monitoring health change of healthcare interventions or technologies among children could be enriched if the EQ-5D-Y proxy version is confirmed its validity in the application.
Conference/Value in Health Info
2025-11, ISPOR Europe 2025, Glasgow, Scotland
Value in Health, Volume 28, Issue S2
Code
MSR60
Topic
Epidemiology & Public Health, Health Policy & Regulatory, Methodological & Statistical Research
Topic Subcategory
PRO & Related Methods
Disease
No Additional Disease & Conditions/Specialized Treatment Areas