Prevalence of Migraine in India: A Meta-Analysis Based on Diagnostic Criteria and Gender Differences
Author(s)
Pranav R. Mhetre, Pharm D1, Tanvi Rajesh Mhetre, Pharm D2, Anjana Barola, PhD3.
1Student, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, India, 2Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, India, 3Dr. D. Y. Patil Institute of Pharmaceutical Sciences & Research, Pimpri, Pimpri, India.
1Student, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, India, 2Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, India, 3Dr. D. Y. Patil Institute of Pharmaceutical Sciences & Research, Pimpri, Pimpri, India.
OBJECTIVES: 1. To estimate the pooled prevalence of migraine in India through a meta-analysis of published studies2. To evaluate how migraine prevalence varies based on the diagnostic criteria used.3. To assess gender-based differences in the prevalence of migraine across the Indian population.
METHODS: A systematic literature search was conducted using PubMed and Google Scholar to identify relevant studies reporting the prevalence of migraine in Indian populations. A random-effects meta-analysis was performed using the DerSimonian and Laird method to account for variability among studies. Subgroup analyses were conducted based on the diagnostic criteria employed and by gender (male vs. female). Statistical heterogeneity was assessed using the I² and τ² statistics, and publication bias was evaluated using Egger’s regression test.
RESULTS: A total of 15 studies were included in the meta-analysis, with a pooled migraine prevalence of 18.19% (95% CI: 17.62-18.77%). Subgroup analysis by diagnostic criteria:
CONCLUSIONS: The prevalence of migraine in India is influenced significantly by the diagnostic criteria used and by gender. The highest prevalence was observed in studies using ICHD-3 criteria and among females. These findings emphasize the need for standardized diagnostic practices and targeted gender-specific migraine management strategies in India.
METHODS: A systematic literature search was conducted using PubMed and Google Scholar to identify relevant studies reporting the prevalence of migraine in Indian populations. A random-effects meta-analysis was performed using the DerSimonian and Laird method to account for variability among studies. Subgroup analyses were conducted based on the diagnostic criteria employed and by gender (male vs. female). Statistical heterogeneity was assessed using the I² and τ² statistics, and publication bias was evaluated using Egger’s regression test.
RESULTS: A total of 15 studies were included in the meta-analysis, with a pooled migraine prevalence of 18.19% (95% CI: 17.62-18.77%). Subgroup analysis by diagnostic criteria:
- ICHD-2 (5 studies): 16.58% (95% CI: 15.72-17.45%)
- ICHD-3 (3 studies): 24.83% (95% CI: 23.79-25.86%)
- ID Migraine (3 studies): 11.89% (95% CI: 10.20-13.58%)
- Not specified (2 studies): 13.22% (95% CI: 11.60-14.83%)
- Males (15 studies): 18.86% (95% CI: 11.24-26.49%, I² = 98.2%, τ² = 178.26)
- Females (15 studies): 26.91% (95% CI: 26.16-27.67%, I² = 99.2%, τ² = 362.21)
CONCLUSIONS: The prevalence of migraine in India is influenced significantly by the diagnostic criteria used and by gender. The highest prevalence was observed in studies using ICHD-3 criteria and among females. These findings emphasize the need for standardized diagnostic practices and targeted gender-specific migraine management strategies in India.
Conference/Value in Health Info
2025-11, ISPOR Europe 2025, Glasgow, Scotland
Value in Health, Volume 28, Issue S2
Code
EPH190
Topic
Epidemiology & Public Health
Disease
Neurological Disorders