Improving Clinical Outcomes in Patients With Advanced Diabetic Foot Ulcers Through Bioimpression Technology

Author(s)

JUAN C. FERNANDEZ MERCADO, MBA, MSc, PhD, MD1, Nelson Alvis-Guzman, MPH, PhD, MD2, Lácides José Barrera C, Sr.3.
1UNIVERSIDAD DE CARTAGENA, Cartagena, Colombia, 2Universidad de Cartagena - ALZAK Foundation, Cartagena, Colombia, 3Gerente de Valor y Acceso, ANNAR Health Technologies – Colombia, Bogotá, Colombia.
OBJECTIVES: This study aimed to evaluate the clinical impact of implementing bioimpression technology in the treatment of advanced diabetic foot ulcers (DFUs) in Colombia. In a country facing an increasing burden of chronic non-communicable diseases, especially diabetes-related complications, improving outcomes such as wound healing and limb preservation is a priority for the health system.
METHODS: We conducted a comparative observational study using clinical data from IPSs in the Caribbean region of Colombia. Patients with Wagner grade III and IV DFUs were treated under two care models: (a) conventional wound care protocols and (b) intervention with bioimpression technology. Key variables included healing time, infection resolution, pain perception, and hospitalization rates. A multidisciplinary team ensured standardization across both models.
RESULTS: Patients managed with bioimpression technology showed a 38% reduction in healing time (p<0.05), a 52% decrease in secondary infection rates, and reported improved pain control and satisfaction with visual healing progress. The approach was especially effective in public institutions with limited access to advanced therapies, demonstrating significant adaptability and potential for scalability in vulnerable populations.
CONCLUSIONS: The integration of bioimpression technology in DFU care significantly improves clinical outcomes, reduces complications, and enhances the patient experience. These findings support the inclusion of bioimpression approaches in national chronic care strategies, particularly in regions such as the Caribbean coast where health access inequalities persist. Future work should explore broader implementation models and integration into capitated care programs with EPSs to promote sustainability and wider impact.

Conference/Value in Health Info

2025-11, ISPOR Europe 2025, Glasgow, Scotland

Value in Health, Volume 28, Issue S2

Code

CO145

Topic

Clinical Outcomes, Economic Evaluation

Topic Subcategory

Clinical Outcomes Assessment, Comparative Effectiveness or Efficacy

Disease

Diabetes/Endocrine/Metabolic Disorders (including obesity), Personalized & Precision Medicine

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