Colorectal Cancer Mortality Overview in Mexico 1998-2023
Author(s)
David isai Palafox Torres, MD1, Marisa Chávez Millán, MD2, Consuelo Escamilla Nuñez, PhD3, Lilia V. Castro Porras, PhD3, Rosalba Rojas Martínez, PhD3.
1National Institute of Public Health, Ciudad de México, Mexico, 2Independent Consultant, Ciudad de México, Mexico, 3Instituto Nacional de Salud Publica, Ciudad de México, Mexico.
1National Institute of Public Health, Ciudad de México, Mexico, 2Independent Consultant, Ciudad de México, Mexico, 3Instituto Nacional de Salud Publica, Ciudad de México, Mexico.
OBJECTIVES: Colorectal cancer (CRC) in Mexico is a significant public health problem due to its high incidence, mortality, and economic burden. In 2018, it was the second leading cause of cancer mortality in both sexes. Globally, the CRC burden is projected to increase by 60% by 2030, with more than 2.2 million new cases and 1.1 million deaths. This study seeks to update the evidence to understand its magnitude and changes in mortality patterns. The objective is to describe the outlook of mortality due to colorectal cancer, from the perspective of mortality trends and years of life lost due to premature death in the population aged 20 years and older in Mexico from 1998-2023, stratified by sex.
METHODS: This longitudinal study uses secondary data on CRC mortality, life expectancy and population projections. Information on malignant neoplasms of the colon (ICD-10 C180, C182-C189) and rectum (C19-C20) comes from INEGI death certificates. CONAPO population projections will complement population distributions by age and sex. Mortality rates and trends will be analyzed with JointPoint Regression, and years of life lost due to premature death were estimated.
RESULTS: From 1998 to 2023, Mexico registered 132,165 CRC deaths in adults aged 20 years and older. During this period, deaths increased from 2,338 to 14,952, with mortality rates ranging from 5.9 to 7.2 per 100,000 population. Males showed higher mortality, with an annual increase of 1.4%, compared to 0.34% in females. Years of life lost due to premature death increased significantly, from 10,876 to 41,022 in men and from 14,396 to 51,603 in women.
CONCLUSIONS: CRC mortality in Mexico significantly increased from 1998 to 2023, underscoring the urgent need to strengthen prevention, early diagnosis, and treatment strategies to mitigate its impact on the population.
METHODS: This longitudinal study uses secondary data on CRC mortality, life expectancy and population projections. Information on malignant neoplasms of the colon (ICD-10 C180, C182-C189) and rectum (C19-C20) comes from INEGI death certificates. CONAPO population projections will complement population distributions by age and sex. Mortality rates and trends will be analyzed with JointPoint Regression, and years of life lost due to premature death were estimated.
RESULTS: From 1998 to 2023, Mexico registered 132,165 CRC deaths in adults aged 20 years and older. During this period, deaths increased from 2,338 to 14,952, with mortality rates ranging from 5.9 to 7.2 per 100,000 population. Males showed higher mortality, with an annual increase of 1.4%, compared to 0.34% in females. Years of life lost due to premature death increased significantly, from 10,876 to 41,022 in men and from 14,396 to 51,603 in women.
CONCLUSIONS: CRC mortality in Mexico significantly increased from 1998 to 2023, underscoring the urgent need to strengthen prevention, early diagnosis, and treatment strategies to mitigate its impact on the population.
Conference/Value in Health Info
2025-11, ISPOR Europe 2025, Glasgow, Scotland
Value in Health, Volume 28, Issue S2
Code
EPH47
Topic
Epidemiology & Public Health
Topic Subcategory
Public Health
Disease
Gastrointestinal Disorders, Oncology