Analysis of the Epidemiological Disease Burden of Endometriosis in Hungary Based on Data From the Global Burden of Disease Study
Author(s)
Luca Fanni Kajos, PhD1, Dalma Pónusz-Kovács, MSc1, Bettina Kovács, MSc1, Tímea Csákvári, PhD2, Róbert Pónusz, PhD1, Diána Elmer, PhD1, József Bódis, MD, PhD, Habil3, Imre Boncz, MSc, PhD, MD1.
1Institute for Health Insurance, Faculty of Health Sciences, University of Pécs, Pécs, Hungary, 2Institute for Health Insurance, Faculty of Health Sciences, University of Pécs, Zalaegerszeg, Hungary, 3National Laboratory on Human Reproduction, University of Pécs, Pécs, Hungary.
1Institute for Health Insurance, Faculty of Health Sciences, University of Pécs, Pécs, Hungary, 2Institute for Health Insurance, Faculty of Health Sciences, University of Pécs, Zalaegerszeg, Hungary, 3National Laboratory on Human Reproduction, University of Pécs, Pécs, Hungary.
OBJECTIVES: Endometriosis is a chronic gynecological condition recognized as one of the most common causes of infertility, affecting approximately 18% of women of reproductive age worldwide. The aim of our study was to examine the epidemiological disease burden of endometriosis in Hungary based on data from the Global Burden of Disease Study (GBD), focusing on the year 2021.
METHODS: The epidemiological disease burden of endometriosis was analysed using the Global Burden of Disease Study (GBD, 2021) Institute for Health Metrics and Evaluation (IHME) database for the year 2021. We assessed the prevalence, incidence, disability-adjusted life years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs) associated with endometriosis at the national level in Hungary.
RESULTS: In 2021, the prevalence of endometriosis in Hungary was 426.65 cases per 100,000 population, while the incidence was 59.83 per 100,000. The number of DALYs was 39.49 per 100,000 population, accounting for 0.09% of total DALYs. YLDs totaled 39.32 per 100,000 population (0.25% of total YLDs), and YLLs amounted to 0.17 per 100,000. The age-standardized prevalence was 480.71 per 100,000, which is higher than the European Union (464.63) and OECD (457.61) averages, but still below the global average (556.98). The highest prevalence rates were observed in the 25-29 age group (1395.32 per 100,000), followed by the 30-34 (1150.26), and 20-24 (1132.94) age groups.
CONCLUSIONS: In summary, although the prevalence of endometriosis in Hungary showed a decreasing trend between 1990 and 2021, the 2021 figures still lag behind the EU and OECD averages. According to health economic analyses, early detection and targeted treatment can reduce the long-term societal and economic burden of the disease. Therefore, prevention, timely diagnosis, and optimal therapy are key components of effective disease management.
METHODS: The epidemiological disease burden of endometriosis was analysed using the Global Burden of Disease Study (GBD, 2021) Institute for Health Metrics and Evaluation (IHME) database for the year 2021. We assessed the prevalence, incidence, disability-adjusted life years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs) associated with endometriosis at the national level in Hungary.
RESULTS: In 2021, the prevalence of endometriosis in Hungary was 426.65 cases per 100,000 population, while the incidence was 59.83 per 100,000. The number of DALYs was 39.49 per 100,000 population, accounting for 0.09% of total DALYs. YLDs totaled 39.32 per 100,000 population (0.25% of total YLDs), and YLLs amounted to 0.17 per 100,000. The age-standardized prevalence was 480.71 per 100,000, which is higher than the European Union (464.63) and OECD (457.61) averages, but still below the global average (556.98). The highest prevalence rates were observed in the 25-29 age group (1395.32 per 100,000), followed by the 30-34 (1150.26), and 20-24 (1132.94) age groups.
CONCLUSIONS: In summary, although the prevalence of endometriosis in Hungary showed a decreasing trend between 1990 and 2021, the 2021 figures still lag behind the EU and OECD averages. According to health economic analyses, early detection and targeted treatment can reduce the long-term societal and economic burden of the disease. Therefore, prevention, timely diagnosis, and optimal therapy are key components of effective disease management.
Conference/Value in Health Info
2025-11, ISPOR Europe 2025, Glasgow, Scotland
Value in Health, Volume 28, Issue S2
Code
EPH16
Topic
Epidemiology & Public Health, Health Policy & Regulatory, Real World Data & Information Systems
Topic Subcategory
Disease Classification & Coding, Public Health
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, Reproductive & Sexual Health