A Health Economic Evaluation Framework for Implementing a Digital Survivorship Passport for Childhood Cancer Survivors

Author(s)

Gerald Gredinger1, Florian Trauner, Dr.2, Ruth Ladenstein, Professor3, Riccardo Haupt, Dr.4, Desiree Grabov, Dr.5, Catherine Chronaki, -6, Hanna Gsell, -7, Julia Balaguer, PhD, MD8, Jelena Rascon, Dr.9, Thorsten Langer, Professor10, Anne Uyttebroeck, Professor11, Timm Lilienthal, -5, Markus Schepers, Dr.5, Anna-Liesa Filbert, -5, Edit Bardi, Dr.3.
1Austrian National Public Health Institute / GÖG, Vienna, Austria, 2Health Economics & Health System Analysis, Austrian National Public Health Institute, Vienna, Austria, 3St. Anna Children’s Cancer Research Institute (St. Anna CCRI), Vienna, Austria, 4IRCCS Istituto Giannina Gaslini (IGG), Genova, Italy, 5UMC Mainz, Mainz, Germany, 6HL7 Europe, Brussels, Belgium, 7Child Cancer International Europe, Vienna, Austria, 8Hospital Universitario La Fe (HULAFE), Valencia, Spain, 9Vilnius University Hospital Santaros Klinikos (VULSK), Vilnius, Lithuania, 10Universitätsklinikum Schleswig-Holstein, Lübeck, Germany, 11University Hospital UZ Leuven, Leuven, Belgium.
OBJECTIVES: The PanCareSurPass project aims to improve survivorship care for children and adolescents diagnosed with cancer across Europe. Despite an 80% survival rate, significant disparities in follow-up care persist. To address this, the project introduces the SurPass v2.0 digital survivorship passport in clinics across Austria, Belgium, Germany, Italy, Lithuania, and Spain. This abstract outlines the development of a health economic evaluation framework to assess the implementation of SurPass v2.0, supported by the EU Horizon 2020 program.The framework serves two main purposes: (1) to compare the outcomes and costs of SurPass v2.0 implementation, and (2) to support evidence-based decision-making at local, regional, and national levels.
METHODS: The framework consists of three components:
  1. Cost Utility Analysis (CUA): Evaluates cost per quality-adjusted life year (QALY) gained using the EQ-5D-5L(-Y) instrument. Cost categories are informed by literature and expert input and include survivor-, provider-, payer-, and system-level costs, further divided into implementation, operational, and patient costs.
  2. Multi-Criteria Decision Analysis (MCDA): Incorporates broader outcomes such as patient activation, education, empowerment, and perceived usefulness. Stakeholder-informed online workshops guide the weighting of criteria.
  3. Prediction Model: Integrates CUA and MCDA results, accounting for country-specific healthcare contexts and digital readiness.

RESULTS: Three cost reporting tools were developed: a hospital-level tool, a healthcare provider survey, and a caregiver/survivor questionnaire. These tools capture detailed cost data and stakeholder perspectives. MCDA produces an overall value score that feeds into the prediction model.
CONCLUSIONS: This framework offers a comprehensive, adaptable approach to evaluating digital implementations such as the survivorship care tool PanCare SurPass v2.0.

Conference/Value in Health Info

2025-11, ISPOR Europe 2025, Glasgow, Scotland

Value in Health, Volume 28, Issue S2

Code

EE18

Topic

Economic Evaluation, Health Policy & Regulatory, Health Service Delivery & Process of Care

Topic Subcategory

Thresholds & Opportunity Cost

Disease

Oncology, Pediatrics

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