Prospective, Comparative Study Between Fully-Automated and Semi-Automated Whole Blood Processing Systems in a Colombian Blood Bank Center
Author(s)
Nil Comasòlivas, MSc, MD1, Angela Soto, Microbiology2, Juan Carlos Calderón, MD2, Sergio Jaramillo Velásquez, MD3, Gloria Eugenia Barco Atehortúa, Microbiology3, Jorge Hernando Donado Gomez, MD3;
1Terumo Blood and Cell Technologies, Head of Market Access and Health Economics LATAM, Zaventem, Belgium, 2Terumo Blood and Cell Technologies, Bogotá, Colombia, 3Hospital Pablo Tobón Uribe, Banco de Sangre, Medellín, Colombia
1Terumo Blood and Cell Technologies, Head of Market Access and Health Economics LATAM, Zaventem, Belgium, 2Terumo Blood and Cell Technologies, Bogotá, Colombia, 3Hospital Pablo Tobón Uribe, Banco de Sangre, Medellín, Colombia
Presentation Documents
OBJECTIVES: The aim of this prospective study is to evaluate and compare quality parameters of final blood products processed with fully-automated (ABPS) versus semi-automated (SABPS) whole blood processing systems.
METHODS: In Hospital Pablo Tobón Uribe Blood Bank, from 20th - 24th November 2023, 80 whole blood bags (WBB) were included in the study. 40 WBB were processed with ABPS, and 40 WBB with SABPS.
3 final blood products were obtained with both systems: Red Cell Concentrates (RCC), Interim Platelet Concentrates (IPU), and Plasma Units (PU).
16 different blood quality parameters were analyzed to obtain mean, standard deviation and p-value.
RESULTS: WBB processed with ABPS vs. SABPS had no statistically significant differences (p-value >0.05) in volume, hemoglobin, hematocrit and leukocyte count.
RCC processed with ABPS vs. SABPS had statistically significant differences (p-value <0.001) in volume (ABPS: 292ml vs. SABPS: 232ml) and hemoglobin (ABPS: 19.1gr/dL vs. SABPS: 18.3gr/dL).
IPU processed with ABPS vs. SABPS had statistically significant differences (p-value <0.001) in volume (ABPS: 62ml vs. SABPS: 59ml), leukocyte count (ABPS: 497 vs. SABPS: 158), red blood cell count (ABPS: 0.0325 vs. SABPS: 0.0186) and platelet count (p-value = 0.005) (ABPS: 1.42E+06 vs. SABPS: 1.17E+06).
PU processed with ABPS and SABPS had statistically significant differences in leukocyte count (p-value <0.001) (ABPS: 0.006 vs. SABPS: 0.015) and red blood cell count (p-value =0.019) (ABPS: 0.0018 vs. SABPS: 0.0030).
CONCLUSIONS: As there were no statistically significant differences in WBB processed with ABPS vs. SABPS, differences found in final blood products were solely based on the system used.
This prospective study objectifies better blood quality in products processed with ABPS vs. SABPS.
In RCC: higher volume and hemoglobin; in IPU: higher volume and platelet count; in PU: lower leukocyte and red blood cell count.
Although IPU processed with ABPS vs. SABPS had higher leukocyte count, both can be safely transfused.
METHODS: In Hospital Pablo Tobón Uribe Blood Bank, from 20th - 24th November 2023, 80 whole blood bags (WBB) were included in the study. 40 WBB were processed with ABPS, and 40 WBB with SABPS.
3 final blood products were obtained with both systems: Red Cell Concentrates (RCC), Interim Platelet Concentrates (IPU), and Plasma Units (PU).
16 different blood quality parameters were analyzed to obtain mean, standard deviation and p-value.
RESULTS: WBB processed with ABPS vs. SABPS had no statistically significant differences (p-value >0.05) in volume, hemoglobin, hematocrit and leukocyte count.
RCC processed with ABPS vs. SABPS had statistically significant differences (p-value <0.001) in volume (ABPS: 292ml vs. SABPS: 232ml) and hemoglobin (ABPS: 19.1gr/dL vs. SABPS: 18.3gr/dL).
IPU processed with ABPS vs. SABPS had statistically significant differences (p-value <0.001) in volume (ABPS: 62ml vs. SABPS: 59ml), leukocyte count (ABPS: 497 vs. SABPS: 158), red blood cell count (ABPS: 0.0325 vs. SABPS: 0.0186) and platelet count (p-value = 0.005) (ABPS: 1.42E+06 vs. SABPS: 1.17E+06).
PU processed with ABPS and SABPS had statistically significant differences in leukocyte count (p-value <0.001) (ABPS: 0.006 vs. SABPS: 0.015) and red blood cell count (p-value =0.019) (ABPS: 0.0018 vs. SABPS: 0.0030).
CONCLUSIONS: As there were no statistically significant differences in WBB processed with ABPS vs. SABPS, differences found in final blood products were solely based on the system used.
This prospective study objectifies better blood quality in products processed with ABPS vs. SABPS.
In RCC: higher volume and hemoglobin; in IPU: higher volume and platelet count; in PU: lower leukocyte and red blood cell count.
Although IPU processed with ABPS vs. SABPS had higher leukocyte count, both can be safely transfused.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
MT40
Topic
Medical Technologies
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, STA: Multiple/Other Specialized Treatments