Presentation (CTI)

OBJECTIVES: To identify strategies for increasing clinical trial participation, particularly for Native Hawaiian (NH), Pacific Islander (PI), and Asian Populations.
METHODS: Key informant eligibility criteria included: 1) experience working with NH, PI, or Asian populations; and 2) fluent in English. Two interviewers conducted 30-minute virtual interviews with 20 key informants. Key informants included clinical researchers, physicians, academicians, and community members, who were recruited based on existing networks and snowball sampling. De-identified transcripts were analyzed using Rapid Qualitative Analysis, which included summarizing interviews in key domains on templates, transferring them to a matrix, and generating key takeaways. Institutional Review Board approval was obtained from The Queen’s Medical Center, Hawaii.
RESULTS: Sixty percent of key informants were women; 25% were between 18 and 39 years; 55% were between 40 and 64 years; and 20% were 65 years or older. A majority (75%) of key informants had more than 10 years of professional experience working with NH, PI, or Asian communities. All key informants surveyed stated that improving access to clinical trials would benefit NH, PI, or Asian communities. Key informants suggested focusing on three main areas for increasing clinical trial participation in NH, PI, and Asian populations: 1) Providing unique accommodations specific to the community’s needs; 2) Addressing historical trauma and medical mistrust; 3) Emphasizing potential community benefits of clinical research.
CONCLUSIONS: Key informants suggested that clinical trial participation can be increased by addressing mistrust, highlighting community benefits, and providing specific accommodations for each community. In addition to these three main areas, the key informants conveyed that it would be critical to maintain a long-term relationship with each of the NH, PI, or Asian communities to continue building trust and their involvement in clinical trials.