Hospital Budget Impact Model of Patterned Frequency-Modulated Oral Stimulation in Preterm Infants
Author(s)
Carla Fernandez Barceló, MPH1, Tobias Muench, MSc1, Rhodri Saunders, BSc, MSc, PhD1, Alex Veloz, MSc2.
1Coreva Scientific GmbH & Co KG, Koenigswinter, Germany, 2HEOR Pro, Chicago, IL, USA.
1Coreva Scientific GmbH & Co KG, Koenigswinter, Germany, 2HEOR Pro, Chicago, IL, USA.
Presentation Documents
OBJECTIVES: Premature childbirth can disrupt the development of essential functions like non-nutritive sucking (NNS), necessary to develop full oral feeding (FOF). Patterned and frequency-modulated oro-somatosensory stimulation (PFOS) promotes NNS development by simulating the natural feeding rhythms of neonates. This study assessed the economic impact of providing PFOS to preterm infants in the US from a hospital perspective.
METHODS: A budget impact model from a hospital perspective was developed, consisting of a decision tree and a semi-Markov model, and comparing PFOS (NTrainer™ system 2.0) to the standard of care. The care pathway from childbirth to 30 days post hospital discharge was modelled for a 1-year cohort of preterm 25-30 GAB newborns (Gestational Age at Birth, in weeks) , and was informed by published literature. The costs for the PFOS system were included in the analysis as a subscription payment. The outcomes of the analysis were total costs (in 2023 USD). Probabilistic and one-way sensitivity analyses were performed to address uncertainty.
RESULTS: For 120 preterm infants born at a GAB of 25-30 weeks, the model resulted in average cost savings of $2,431,017 (95% CrI $5,503,174 - -$746,743), when comparing PFOS to the standard of care (total costs: $24,461,930 vs. $26,892,947, respectively). The PFOS system cost was less than 2% of the total cost for the intervention arm. PFOS was cost-saving in 93.5% of the 1,500 Monte Carlo simulations. The main drivers were time to achieve full oral feed, and the percentage of newborns discharged with full oral feed.
CONCLUSIONS: This study found PFOS to reduce the hospital associated costs for preterm infants in the US due to reduced time to full oral feed and length of NICU stay.
METHODS: A budget impact model from a hospital perspective was developed, consisting of a decision tree and a semi-Markov model, and comparing PFOS (NTrainer™ system 2.0) to the standard of care. The care pathway from childbirth to 30 days post hospital discharge was modelled for a 1-year cohort of preterm 25-30 GAB newborns (Gestational Age at Birth, in weeks) , and was informed by published literature. The costs for the PFOS system were included in the analysis as a subscription payment. The outcomes of the analysis were total costs (in 2023 USD). Probabilistic and one-way sensitivity analyses were performed to address uncertainty.
RESULTS: For 120 preterm infants born at a GAB of 25-30 weeks, the model resulted in average cost savings of $2,431,017 (95% CrI $5,503,174 - -$746,743), when comparing PFOS to the standard of care (total costs: $24,461,930 vs. $26,892,947, respectively). The PFOS system cost was less than 2% of the total cost for the intervention arm. PFOS was cost-saving in 93.5% of the 1,500 Monte Carlo simulations. The main drivers were time to achieve full oral feed, and the percentage of newborns discharged with full oral feed.
CONCLUSIONS: This study found PFOS to reduce the hospital associated costs for preterm infants in the US due to reduced time to full oral feed and length of NICU stay.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
MT36
Topic
Medical Technologies
Disease
SDC: Pediatrics, STA: Nutrition