Gender-Based Gaps In Access to Tricuspid Valve Interventions In England
Author(s)
Jana Boleckova, PhD1, Alexis Hagenstein, MSc2, Matteo Vernia, MSc3, Jeff Stonadge, BSc4, Rachele Busca, MSc, PharmD5, Sylvie Nichols, BComm, MBA, MSc6.
1Edwards Lifesciences, Prague, Czech Republic, 2Edwards Lifesciences, Paris, France, 3Edwards Lifesciences, Milan, Italy, 4Edwards Lifesciences, Newbury, United Kingdom, 5Edwards Lifesciences, Nyon, Switzerland, 6Edwards Lifesciences Canada, Mississauga, ON, Canada.
1Edwards Lifesciences, Prague, Czech Republic, 2Edwards Lifesciences, Paris, France, 3Edwards Lifesciences, Milan, Italy, 4Edwards Lifesciences, Newbury, United Kingdom, 5Edwards Lifesciences, Nyon, Switzerland, 6Edwards Lifesciences Canada, Mississauga, ON, Canada.
Presentation Documents
OBJECTIVES: Tricuspid valve disease affects the valve between the heart’s right atrium and right ventricle. Despite a significant increase in the prevalence of tricuspid valve diseases and a documented higher prevalence in females, there has not been a corresponding rise in treatment interventions. This retrospective database analysis aims to explore gender differences in the care of patients with tricuspid valve diseases in England.
METHODS: We retrospectively identified adults over 55 years who underwent tricuspid valve interventions from the English Hospital Episode Statistics (HES) between September 2019 and August 2024. The interventions were categorized using 12 different OPCS codes, including tricuspid replacement, repair, repositioning, valvotomy, valvectomy, and annuloplasty. The cohort was analyzed for hospitalization prior to the index for any reason, or for diseases of the circulatory system, all categorized by age and gender.
RESULTS: Over the 66-month period, 4,295 patients aged over 55 years underwent tricuspid valve interventions. Among these, 4,180 patients, both male and female, up to age 89 years, were analyzed to identify gender disparities. Overall, 57% of the treated patients were male, while 43% female. The number of cases peaked at 1,105 in the 75-79 age group, with 45% being female. The most frequent primary diagnoses were combined disorders of multiple valves. Hospital admissions prior to tricuspid intervention for diseases of the circulatory system were primarily due to multiple valve diseases (I08), non-rheumatic mitral valve disorder (I34), chronic ischemic heart diseases (I25), atrial fibrillation and flutter (I48), and heart failure (I50), corroborating a higher hospitalization rate of males compared to females.
CONCLUSIONS: Among patients receiving tricuspid valve interventions, males were more prevalent at the index and in prior hospitalizations. These treatment disparities do not reflect the epidemiology of TR, for which females are 3 times more likely to suffer from TR disorders after age 70 than males.
METHODS: We retrospectively identified adults over 55 years who underwent tricuspid valve interventions from the English Hospital Episode Statistics (HES) between September 2019 and August 2024. The interventions were categorized using 12 different OPCS codes, including tricuspid replacement, repair, repositioning, valvotomy, valvectomy, and annuloplasty. The cohort was analyzed for hospitalization prior to the index for any reason, or for diseases of the circulatory system, all categorized by age and gender.
RESULTS: Over the 66-month period, 4,295 patients aged over 55 years underwent tricuspid valve interventions. Among these, 4,180 patients, both male and female, up to age 89 years, were analyzed to identify gender disparities. Overall, 57% of the treated patients were male, while 43% female. The number of cases peaked at 1,105 in the 75-79 age group, with 45% being female. The most frequent primary diagnoses were combined disorders of multiple valves. Hospital admissions prior to tricuspid intervention for diseases of the circulatory system were primarily due to multiple valve diseases (I08), non-rheumatic mitral valve disorder (I34), chronic ischemic heart diseases (I25), atrial fibrillation and flutter (I48), and heart failure (I50), corroborating a higher hospitalization rate of males compared to females.
CONCLUSIONS: Among patients receiving tricuspid valve interventions, males were more prevalent at the index and in prior hospitalizations. These treatment disparities do not reflect the epidemiology of TR, for which females are 3 times more likely to suffer from TR disorders after age 70 than males.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
EPH183
Topic
Epidemiology & Public Health
Topic Subcategory
Public Health
Disease
SDC: Cardiovascular Disorders (including MI, Stroke, Circulatory)