Epidemiological Estimates of Interstitial Lung Diseases in Mexico: A Real-World Data Analysis of 2,591,278 Hospital Discharges From the Ministry of Health
Author(s)
David Rodriguez, MD., MSc., Rebeca Garcia-Toto, MD., Berenice Lopez, MD.;
Boehringer Ingelheim, Mexico City, Mexico
Boehringer Ingelheim, Mexico City, Mexico
OBJECTIVES: To provide epidemiological estimates of interstitial lung diseases (ILD)-related ICD-10 codes using Real-World Data (RWD) from the 2023 Mexican Ministry of Health (MoH) hospitals discharge dataset at a national level.
METHODS: We retrospectively analyzed ILD discharges in the 2023 MoH open database using four ILD-related ICD-10 codes (J840 - alveolar and perialveolar conditions, J841 - other interstitial pulmonary diseases with fibrosis, J848 - interstitial pulmonary disease, unspecified, and J849 - interstitial pulmonary disease, unspecified). In addition to demographic variables, geographic distribution, discharge motive, and social security affiliation data were collected. We developed an interactive dashboard specifically designed for data analysis and visualization.
RESULTS: From a total of 2,591,278 discharges reported in the MoH 2023 database, 924 (0.03%) were related to ILD. Interstitial pulmonary disease, unspecified (J849) and other interstitial pulmonary disease with fibrosis (J841) were the conditions with the highest number of hospital discharges, 487 (52.7%) and 379 (41%), respectively. Male sex was predominant (51.1%), median age 65 years (IQR 53-76). Most of the discharges were incidental (93.2%), and the vast majority occurred in Central (52.9%) and Southern (25.4%) regions. Improvement was the main reason for discharge (78.3%), followed by death (16%), and voluntary discharge (2.3%). In most of the events (74.5%), the social security affiliation was unknown (31.4%), were not affiliated (30.1%), or were unspecified (13%). These observations were mainly consistent across all the ICD-10 codes analyzed.
CONCLUSIONS: Through our real-world data analysis, ILD are underdiagnosed across the nation, with at least one in three events lacking social security coverage, highlighting critical gaps in the management for these conditions. Location of specialized care centers in Mexico may partially explained geographic distribution of events. ILD are rare and complex diseases that require strengthening epidemiological surveillance, health care infrastructure at all levels to optimize early diagnosis and referral, treatment access, and disease prognosis.
METHODS: We retrospectively analyzed ILD discharges in the 2023 MoH open database using four ILD-related ICD-10 codes (J840 - alveolar and perialveolar conditions, J841 - other interstitial pulmonary diseases with fibrosis, J848 - interstitial pulmonary disease, unspecified, and J849 - interstitial pulmonary disease, unspecified). In addition to demographic variables, geographic distribution, discharge motive, and social security affiliation data were collected. We developed an interactive dashboard specifically designed for data analysis and visualization.
RESULTS: From a total of 2,591,278 discharges reported in the MoH 2023 database, 924 (0.03%) were related to ILD. Interstitial pulmonary disease, unspecified (J849) and other interstitial pulmonary disease with fibrosis (J841) were the conditions with the highest number of hospital discharges, 487 (52.7%) and 379 (41%), respectively. Male sex was predominant (51.1%), median age 65 years (IQR 53-76). Most of the discharges were incidental (93.2%), and the vast majority occurred in Central (52.9%) and Southern (25.4%) regions. Improvement was the main reason for discharge (78.3%), followed by death (16%), and voluntary discharge (2.3%). In most of the events (74.5%), the social security affiliation was unknown (31.4%), were not affiliated (30.1%), or were unspecified (13%). These observations were mainly consistent across all the ICD-10 codes analyzed.
CONCLUSIONS: Through our real-world data analysis, ILD are underdiagnosed across the nation, with at least one in three events lacking social security coverage, highlighting critical gaps in the management for these conditions. Location of specialized care centers in Mexico may partially explained geographic distribution of events. ILD are rare and complex diseases that require strengthening epidemiological surveillance, health care infrastructure at all levels to optimize early diagnosis and referral, treatment access, and disease prognosis.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
RWD148
Topic
Real World Data & Information Systems
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, SDC: Rare & Orphan Diseases, SDC: Respiratory-Related Disorders (Allergy, Asthma, Smoking, Other Respiratory)