Descriptive Analysis Of Patients With Psoriasis (PSO) Using Biologics Vs. Non-biologics

Author(s)

Sahar Syed, BS1, Staci Bell, MS2, Krisha Patel, BS, MPH1, Mohammed Deeb, MD1, Scott Chavers, PhD1;
1Walgreens Real World Evidence Clinical Trials, Pharmacoepidemiology, Deerfield, IL, USA, 2Walgreens Real World Evidence Clinical Trials, Data Sciences, Deerfield, IL, USA

Presentation Documents

OBJECTIVES: Patients may use treatment options including biologics and non-biologics to treat plaque psoriasis. Biologics are more expensive than non-biologics which may be a barrier to treatment. This research aims to describe the demographic characteristics, healthcare utilization, and costs among patients with psoriasis who use biologics vs non-biologics
METHODS: This study utilized pharmacy data from the Walgreens Retail Pharmacy Database. Participants with psoriasis with a prescription for biologics or non-biologics were identified between January 1, 2023, and December 31, 2023. No statistical comparisons were conducted as this study was descriptive.
RESULTS: There were 3,582 individuals with psoriasis who used biologics vs. 170,212 individuals who used non-biologics in the pharmacy data. Individuals who used non-biologics were slightly older than those who used biologics (56 years vs. 52 years). 56.8% of those using non-biologics were male vs. 44.8% of those using biologics. Over 50% of participants in both groups were White. Most participants using non-biologics were from the South (39.8%) vs. 40.8% of participants using biologics either had missing regional data or were from Puerto Rico. 91,741 (52.3%) of participants using non-biologics had commercial insurance vs.1,078 (25.6%) of participants using biologics who used commercial insurance as their primary insurance. Notably, 50% of participants using biologics had a government insurance type as their primary insurance. Distributions of provider type among both groups were similar. However, more participants using biologics saw a rheumatologist compared to those using non-biologics (41.9% vs 29.2%). Biologic users incurred a median monthly out-of-pocket cost of $27.48 compared to $14.49 for non-biologic users.
CONCLUSIONS: Individuals who used biologics were slightly younger, more likely to be female, overwhelmingly used the government insurance type, had more rheumatologist visits, and had higher median out-of-pocket costs. This research underscores the possible impact of insurance type, utilization, and costs on differences in plaque psoriasis treatment.

Conference/Value in Health Info

2025-05, ISPOR 2025, Montréal, Quebec, CA

Value in Health, Volume 28, Issue S1

Code

EE511

Topic

Economic Evaluation

Disease

SDC: Systemic Disorders/Conditions (Anesthesia, Auto-Immune Disorders (n.e.c.), Hematological Disorders (non-oncologic), Pain), STA: Biologics & Biosimilars

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