Race and Ethnicity Differences in the HPV Vaccine Initiation Prompted by Electronic Reminders

Author(s)

Tong Han Chung, MPH, PhD1, Yunbo Xie, MS1, Kathleen Hanley, DrPH1, Sandra Stansberry, MPH1, Robert J. Yetman, MD2, Lewis E. Foxhall, MD3, Rosalind Bello, MA3, Yen-Chi Le, PhD1;
1McGovern Medical School, The University of Texas Health Science Center at Houston  at Houston, Department of Healthcare Transformation Initiatives, Houston, TX, USA, 2McGovern Medical School, The University of Texas Health Science Center at Houston  at Houston, Department of Pediatrics, Houston, TX, USA, 3The University of Texas MD Anderson Cancer Center, Office of Health Policy, Houston, TX, USA

Presentation Documents

OBJECTIVES: To assess differences in HPV vaccination initiation by race/ethnicity after an electronic reminder intervention.
METHODS: As a quality improvement project, we applied a pragmatic randomized controlled study design and sent personalized, electronic HPV vaccine reminders with provider recommendation to patients ages 9 to 25 who had not completed their HPV vaccinations. We then compared the HPV vaccine initiation (i.e., yes/no) after the electronic reminders were sent among different race/ethnicity groups. Univariate and multivariable logistic regression analysis was conducted to compare the HPV vaccine initiation by race/ethnicity.
RESULTS: Among 7408 vaccine-eligible patients, 1942 had not initiated HPV vaccination and received up to 3 electronic reminders. Almost 50% of patients were aged 19-26 and 56% were female. Additionally, 61.4% of patients had managed care insurance. Non-Hispanic Black (Odds Ratio (OR): 1.91, 95% CI: 1.13-3.23) and Hispanic (OR: 1.80, 95% CI: 1.09-2.99) were significantly more likely to initiate the HPV vaccine after the electronic reminders were sent compared to Non-Hispanic White. Patients aged 9-14 years (OR: 7.46, 95% CI: 4.69-11.86) and aged 15-18 years (OR: 2.81, 95% CI: 1.60-4.94) were 7.5 and 2.8 times more likely to initiate their HPV vaccination after the electronic reminders were sent compared with patients aged 19-26 years.
CONCLUSIONS: Our results suggest that personalized, electronic reminders that incorporate provider recommendation for HPV vaccination could help improve HPV vaccine initiation among Non-Hispanic Black and Hispanic individuals, especially those who are younger. Future studies should further explore how electronic reminders and tailored messaging content (i.e., provider recommendation, education) may influence the difference in HPV vaccine initiation by race and ethnicity.

Conference/Value in Health Info

2025-05, ISPOR 2025, Montréal, Quebec, CA

Value in Health, Volume 28, Issue S1

Code

MT35

Topic

Medical Technologies

Topic Subcategory

Digital Health

Disease

STA: Vaccines

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