Global Analysis of the Epidemiological Burden of Osteoarthritis based on Data from the Global Burden of Disease Study
Moderator
Luca F Kajos, MASc, MSc, University of Pécs, Doctoral School of Health Sciences, BUDAPEST, Hungary
Speakers
Bálint Molics, MSc, PhD; Dalma Pónusz-Kovács, MSc, University of Pécs, Budapest, Hungary; Bettina Kovács, BSc, MSc, University of Pécs, BUDAPEST, Hungary; Tímea Csákvári, MSc; Róbert Pónusz, MSc, PhD; József Bódis; Imre Boncz, MSc, PhD, MD, University of Pécs, Pécs, Hungary
OBJECTIVES: Osteoarthritis (OA) is the 7th most common cause of disability among individuals aged 70 years and older. The aim of the study was to analyse the global epidemiological disease burden of osteoarthritis, based on data from the Global Burden of Disease Study, focusing on the year 2021.
METHODS: The epidemiological disease burden of osteoarthritis was analysed using the dataset from the Global Burden of Disease Study (GBD, 2021) provided by the Institute for Health Metrics and Evaluation (IHME) database for the year 2021. For the selected condition, we examined prevalence, incidence, disability-adjusted life years (DALYs), and years lived with disability (YLDs) at a global level, disaggregated by sex, age group, and types of osteoarthritis.
RESULTS: In 2021, the prevalence of osteoarthritis was 7.96%, representing 7,691.83 cases per 100,000 population. The age-standardized prevalence was 7.24% (6,967.29 per 100,000 population). The incidence was 590.93 per 100,000 population. Disability-adjusted life years (DALYs) due to osteoarthritis amounted to 269.97 per 100,000 population, representing 0.73% of total global DALYs. Years lived with disability (YLDs) corresponded to 21,304,565.82 years, accounting for 2.33% of total global YLDs. The prevalence of osteoarthritis was higher among women and increased with age. The joints most commonly affected were the knee (4.91%) and the hand (2.55%), with a lower prevalence observed in hip osteoarthritis (0.47%).
CONCLUSIONS: Osteoarthritis imposes a significant global burden, particularly among older adults, with a prevalence of 7.96% in 2021 and notable impacts on disability and quality of life. The findings highlight the need for targeted strategies to address the high prevalence in women and the increasing burden with age, especially in knee and hand osteoarthritis.
METHODS: The epidemiological disease burden of osteoarthritis was analysed using the dataset from the Global Burden of Disease Study (GBD, 2021) provided by the Institute for Health Metrics and Evaluation (IHME) database for the year 2021. For the selected condition, we examined prevalence, incidence, disability-adjusted life years (DALYs), and years lived with disability (YLDs) at a global level, disaggregated by sex, age group, and types of osteoarthritis.
RESULTS: In 2021, the prevalence of osteoarthritis was 7.96%, representing 7,691.83 cases per 100,000 population. The age-standardized prevalence was 7.24% (6,967.29 per 100,000 population). The incidence was 590.93 per 100,000 population. Disability-adjusted life years (DALYs) due to osteoarthritis amounted to 269.97 per 100,000 population, representing 0.73% of total global DALYs. Years lived with disability (YLDs) corresponded to 21,304,565.82 years, accounting for 2.33% of total global YLDs. The prevalence of osteoarthritis was higher among women and increased with age. The joints most commonly affected were the knee (4.91%) and the hand (2.55%), with a lower prevalence observed in hip osteoarthritis (0.47%).
CONCLUSIONS: Osteoarthritis imposes a significant global burden, particularly among older adults, with a prevalence of 7.96% in 2021 and notable impacts on disability and quality of life. The findings highlight the need for targeted strategies to address the high prevalence in women and the increasing burden with age, especially in knee and hand osteoarthritis.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
EPH63
Topic
Epidemiology & Public Health
Topic Subcategory
Public Health
Disease
SDC: Injury & Trauma, SDC: Musculoskeletal Disorders (Arthritis, Bone Disorders, Osteoporosis, Other Musculoskeletal), STA: Surgery