A Reduction in Prosthetic Joint Infection and Surgical Time. Evidence from a Large US Database Study for OR3O Implant System in Hip Revision.
Author(s)
Boxuan Li, MSc, Leo M. Nherera, BSc, MSc, PhD;
Smith + Nephew, Fort Worth, TX, USA
Smith + Nephew, Fort Worth, TX, USA
Presentation Documents
OBJECTIVES: Healthcare costs for hip arthroplasty are rising, with most studies focusing on primary procedures and limited data on hip revision. However, little has been done on hip revision procedures. OR3OTM* with oxidized zirconium (OxZr), hereafter referred to as OR30, is designed to improve the clinical outcomes and economic impacts of hip revision procedures. This study compared the short-term resource utilization of the OR3O revision system with non-OR3O systems.
METHODS: Hip revisions performed from November 2016 to March 2024 were analyzed using the Premier PINC AI Healthcare database. Patients aged ≥21 years with a 6-month baseline and 12-month follow-up period were included; exclusions applied for missing gender, race, or cost data. OR3O device use was identified via appropriate ICD-10-PCS codes and billing records. A 1:3 propensity score matching was executed to facilitate the comparability, followed by generalized regression models assessing the outcome differences between interventions.
RESULTS: The study matched 505 OR3O with 1504 non-OR3O patients, with well-balanced baseline variables. Patients treated with the OR3O were less likely to have periprosthetic joint Infection/wound Infection (odds ratio [OR] 0.69, 95% confidence interval [CI] 0.48-0.97, p=0.037), infection & inflammatory reaction (OR 0.6, CI 0.48-0.75, p<0.001) within one year, and sepsis/septicemia/shock odds within 180 days after procedures (OR 0.65, CI 0.43-0.94, p=0.027). They also had reduced length of stay at the index visit (4.45 versus 5.23 days, p=0.022) and shorter surgery time (254.62 versus 277.96 minutes, p=0.044) compared with non-OR3O patients.
CONCLUSIONS: The OR3O system with OxZr in hip revision demonstrates statistically superior resource use and clinical outcomes compared to non-OR3O systems. This is important in an age when providers are expected to provide quality services at reduced budgets, and when patients need options to lower the risk of complications following surgery.
*Trademark of Smith+Nephew. All Trademarks acknowledged.
METHODS: Hip revisions performed from November 2016 to March 2024 were analyzed using the Premier PINC AI Healthcare database. Patients aged ≥21 years with a 6-month baseline and 12-month follow-up period were included; exclusions applied for missing gender, race, or cost data. OR3O device use was identified via appropriate ICD-10-PCS codes and billing records. A 1:3 propensity score matching was executed to facilitate the comparability, followed by generalized regression models assessing the outcome differences between interventions.
RESULTS: The study matched 505 OR3O with 1504 non-OR3O patients, with well-balanced baseline variables. Patients treated with the OR3O were less likely to have periprosthetic joint Infection/wound Infection (odds ratio [OR] 0.69, 95% confidence interval [CI] 0.48-0.97, p=0.037), infection & inflammatory reaction (OR 0.6, CI 0.48-0.75, p<0.001) within one year, and sepsis/septicemia/shock odds within 180 days after procedures (OR 0.65, CI 0.43-0.94, p=0.027). They also had reduced length of stay at the index visit (4.45 versus 5.23 days, p=0.022) and shorter surgery time (254.62 versus 277.96 minutes, p=0.044) compared with non-OR3O patients.
CONCLUSIONS: The OR3O system with OxZr in hip revision demonstrates statistically superior resource use and clinical outcomes compared to non-OR3O systems. This is important in an age when providers are expected to provide quality services at reduced budgets, and when patients need options to lower the risk of complications following surgery.
*Trademark of Smith+Nephew. All Trademarks acknowledged.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
SA18
Topic
Study Approaches
Disease
SDC: Musculoskeletal Disorders (Arthritis, Bone Disorders, Osteoporosis, Other Musculoskeletal), STA: Surgery