Mission
To curate an ongoing dialog regarding issues around creating, disseminating, sharing, evaluating, and updating open source cost-effectiveness and comparative effectiveness models.
Goal
- Define the issues surrounding open source models
- Improve model transparency, updating, idea exchange, currency, and policy development
- Provide a centralized platform to facilitate discussion and dissemination of information on the topic of open source models
Background
The world is moving towards more openness, sharing, and collaboration. There has been a marked growth in open science; however, there is currently no efficient process for creating, sharing, evaluating, and updating health economic models. This situation can result in the expensive re-creation of existing models or the inappropriate use of outdated models. Moreover, models are often not updated at all. To address these issues, certain institutions have begun to promote and encourage access to open source models and some journals make models available to reviewers upon their request. However, it is unclear how these various groups will encourage widespread model openness and transparency in a repository or otherwise, given intellectual property (IP) rights, costs to initiate and sustain, and legal, information technology, and other issues surrounding such an endeavor. This Special Interest Group has therefore been founded to address these and other challenges and aspects related to the concept of open source models.
Manuscript and Reports
Journal Club
- "CDX2 Biomarker Testing and Adjuvant Therapy for Stage II Colon Cancer: An Exploratory Cost-Effectiveness Analysis" October 2022
- "Simulating Progression-Free and Overall Survival for First-Line Doublet Chemotherapy with or without Bevacizumab in Metastatic Colorectal Cancer Patients Based on Real-World Registry Data" June 2022
- "Cost-effectiveness of Magnetic Resonance Imaging in Prostate Cancer Screening: A Microsimulation Study" March 2022
- “Assessing cost-effectiveness of early intervention in Alzheimer's disease: An open-source modeling framework“ November 2021
- “Development and Validation of the Evaluation Platform in COPD (EPIC): A Population-Based Outcomes Model of COPD for Canada” March 2021
- Putting Stakeholder Engagement at the Center of Health Economic Modeling for Health Technology Assessment in the United States (Downloadable PPT)
Leadership
Chair-Elect
Xavier Pouwels, MSc
Chair
Raymond Henderson
Past Chair
Christopher Sampson, MSc, BA
Working Groups
Member Engagement
Co-Chairs:
Renée Arnold, PharmD, RPh
Ramesh Bhandari
Talitha Feenstra, PhD
Ron Handels
Stephanie Harvard
Tim Wrightson, BSc
Key Project
The Why, How, and Who of an Open-Source Future
Co-Chairs
Xavier Pouwels, MSc
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