Translation, Cross-Cultural Adaptation and Psychometric Testing of a Yoruba Version of the EQ-5D Questionnaire in Patients with Musculoskeletal Disorders


Fatoye F1, Gebrye T2, Fatoye C2, Oyewole O3, Akinfala A3, Ojelade T3, Mbada C4
1Manchester Metropolitan University, Manchester, LIN, UK, 2Manchester Metropolitan University, Manchester, LAN, UK, 3Obafemi Awolowo University, Ile-Ife, Nigeria, 4Obafemi Awolowo University, Ile-Ife,, Nigeria

OBJECTIVES: The EQ-5D is a self-administered questionnaire which necessitates its existence and adaptation in different languages. This study aimed to translate, cross-culturally adapt, and determine the reliability and validity of the Yoruba version of the EQ-5D questionnaire.

METHODS: Following the International Quality of Life Assessment (IQOLA) project guidelines, the EQ-5D-5L questionnaire was first translated from the English version following a sequence of forward translation, reconciliation and harmonization, backward translation, reconciliation of problematic items. A total of 113 individuals with musculoskeletal disorders were recruited to test the validity of the Yoruba translated version of the EQ-5D-5L (EQ-5D-Yor). A seven-day test-retest reliability of the EQ-5D-Yor was carried out among 109 of the respondents. Convergent and discriminant validity of the EQ-5D-Yor were determined using the Yoruba version of the SF-12 (SF-12-Y) and Visual Analogue Scale (VAS). Data was analyzed using descriptive and inferential statistics of Pearson/Spearman correlation, Intra-Class Correlation, Cronbach alpha and multi trait scaling analysis. Alpha level was set as p < 0.05.

RESULTS: The construct validity of the EQ-5D-Yor yielded Spearman rho ranging from 0.438 to 1.000, with the EQ-VAS having the highest co-efficient (r = 1.000; p = 0.001). The convergent validity of the EQ-5D-Yor index with SF-12-Y yielded no significant correlations (p < 0.05), except the physical functioning scale (r = -0.709, p = 0.001). On the other hand, the divergent validity of the EQ-5D-Yor index with VAS yielded a weak correlation, (r = 0.016). The Intra-class Correlation Coefficient and Cronbach alpha for the test-retest reliability of the EQ-5D-Yor were 1.000 and 0.968. The confirmatory factor analysis showed the factor loadings were poor when including VAS in the model.

CONCLUSIONS: The EQ-5D-Yor has acceptable validity and reliability and can be used as a valid tool in economic evaluation studies to assess health benefits in terms of quality adjusted life years among Yoruba speaking population.

Conference/Value in Health Info

2022-05, ISPOR 2022, Washington, DC, USA

Value in Health, Volume 25, Issue 6, S1 (June 2022)




Clinical Outcomes, Economic Evaluation, Epidemiology & Public Health

Topic Subcategory

Clinical Outcomes Assessment, Cost-comparison, Effectiveness, Utility, Benefit Analysis, Public Health


Musculoskeletal Disorders

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