Health-Related Quality of Life and Its Determinants Among Individuals With Spinal Cord Injury in China: Exploratory Analyses From Two National Surveys
Author(s)
Chengaxin Duan, MSc1, Fan Zhang, MSc1, Min Xie, BSc2, Xiao Wen Luah, MSc3, Sijie Han, MSc2, Lu Tian, BSc4.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
OBJECTIVES: To evaluate the health-related quality of life (HRQoL) and its determinants among individuals with spinal cord injury (SCI) in China, using real-world data from two nation-wide surveys conducted in 2020 and 2023.
METHODS: Two cross-sectional surveys were conducted across China in 2020 (n=2,983) and 2023 (n=3,027). Community-dwelling individuals with SCI were invited to complete the electronic questionnaire. Data collected included sociodemographic information, injury characteristics, bladder management, complications, healthcare utilization, and HRQoL measured using the Short Form-36 questionaire. HRQoL was reported via Physical Health Composite (PHC) and Mental Health Composite (MHC) scores. Descriptive statistics were performed to characterize the sample population. Variables associated with PHC and MHC were explored using univariate and multivariate linear regressions.
RESULTS: Respondents’ mean ages were 45 and 46 years-old. Most respondents were male, paraplegic, had thoracic-level injuries, were wheelchair dependent, and required caregivers.Average PHC and MHC scores were 119.68 and 178.00, respectively. Multivariate regression analyses identified income to be positively associated with PHC and MHC scores. Conversely, caregiver dependency, reduced fluid intake, frequent UTIs, prophylactic antibiotic use, renal dysfunction, urethral stricture, and difficulty with self-transfer were negatively associated with PHC and MHC scores. Notably, longer injury duration was positively associated with MHC.
CONCLUSIONS: These identified variables could influence HRQoL among people with SCI in China and may warrant further attention in rehabilitation follow-up. Finally, additional research is needed to validate these exploratory findings.
METHODS: Two cross-sectional surveys were conducted across China in 2020 (n=2,983) and 2023 (n=3,027). Community-dwelling individuals with SCI were invited to complete the electronic questionnaire. Data collected included sociodemographic information, injury characteristics, bladder management, complications, healthcare utilization, and HRQoL measured using the Short Form-36 questionaire. HRQoL was reported via Physical Health Composite (PHC) and Mental Health Composite (MHC) scores. Descriptive statistics were performed to characterize the sample population. Variables associated with PHC and MHC were explored using univariate and multivariate linear regressions.
RESULTS: Respondents’ mean ages were 45 and 46 years-old. Most respondents were male, paraplegic, had thoracic-level injuries, were wheelchair dependent, and required caregivers.Average PHC and MHC scores were 119.68 and 178.00, respectively. Multivariate regression analyses identified income to be positively associated with PHC and MHC scores. Conversely, caregiver dependency, reduced fluid intake, frequent UTIs, prophylactic antibiotic use, renal dysfunction, urethral stricture, and difficulty with self-transfer were negatively associated with PHC and MHC scores. Notably, longer injury duration was positively associated with MHC.
CONCLUSIONS: These identified variables could influence HRQoL among people with SCI in China and may warrant further attention in rehabilitation follow-up. Finally, additional research is needed to validate these exploratory findings.
Conference/Value in Health Info
2025-09, ISPOR Real-World Evidence Summit 2025, Tokyo, Japan
Value in Health Regional, Volume 49S (September 2025)
Code
RWD66
Topic Subcategory
Health & Insurance Records Systems
Disease
SDC: Injury & Trauma