Depression Screening With Validated Thai Depression Inventory (TDI), Lam Employment Absence and Productivity Scale (LEAPS) and World Health Organization Quality of Life (WHOQOL-BREF) Among Private Voluntary Participants and Government Civil Servant...
Author(s)
Wantana Reanmongkol, BPharm, MPharm, PhD1, Chonthicha Tasarach, Pharm.D.2, Piyachat Macharoon, Pharm.D.2, Krittapas Charoenphanich, B.A., Pharm.D.2, Anan Udombhornprabha, BPharm, MBA, MPharm,MSCE, PhD3.
1Pharmacy Practices and Pharmaceutical care, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand, 2Pharmacy Services, Faculty of Pharmacy Western University, Bangkok, Thailand, 3Social and Administrative Pharmacy Practices, Faculty of Pharmacy Western University, Bangkok, Thailand.
1Pharmacy Practices and Pharmaceutical care, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand, 2Pharmacy Services, Faculty of Pharmacy Western University, Bangkok, Thailand, 3Social and Administrative Pharmacy Practices, Faculty of Pharmacy Western University, Bangkok, Thailand.
OBJECTIVES: Economic disruption and subsequent inadequate economic remedy had brought nationwide depressive episodes among underprivileged individuals. Early screening of depression would support further lifesaving.
METHODS: We attempted depression screening among workers using validated patient report outcomes(PROs) Thai version, TDI, LEAPS and WHOQOL-BREF. Voluntary participants recruitment as per IRB approval with consent informed obtained via convenient sampling. PROs scale reliability test using Cronbach’s Alpha correlation coefficient. Test score results were compared with that of civil servant participants as controlled. Statistical analysis employed independent t-test, score correlation employed Pearson correlation coefficient.
RESULTS: Overall 60 individuals, 30 each had regular salary income and non-regular income as compared with 30 civil servants with mean(SD) age in years of 30.4(19.6) vs 36.6(10.8). Other demographics, medical history collected were compared and not statistically significant different. The Cronbach’s alpha correlation coefficient for TDI, LEAPS and WHOQOL-BREF were 0.904,0.907 and 0.938 respectively. The PROs score of individuals vs controlled for total mean(SD) of TDI 18.10(9.98) vs 6.53(5.31) was statistically significant different, p=0.001. These scores suggestive of minor, mild to moderate depression with number(%) were 6(10%), 9(15%) and 4 (6.7%) vs controlled 1(3%), p=0.001 by independent t-test. Total mean(SD) of LEAPS 1.95(1.01) vs 4.60(4.55) suggestive of minimal, minor and moderate mental health insufficiency were significant different as compared with controlled with number(%) of 46 (75.0%), 11(18.5%),4(6.6%) vs 27(90.0%), 3(10%) and 0(0%) at p=0.001. The WHOQOL-BREF reflected a standardized score in mean(SD) with 59.96(15.86) vs 71.76(11.88), were statistically significant with p=0.001. TDI and LEAPS are highly correlated with Pearson correlation coefficient of 0.664 whereas TDI vs WHOQOL-BREF and LEAPS vs WHOQOL-BREF reflected Pearson correlation coefficient of -0.730 and -0.671 respectively.
CONCLUSIONS: This investigation employed validated Thai version of TDI, LEAPS and WHOQOL-BREF were robust, reliable with predicted incidence of mild- moderate depression could be as high as 25% as compared with 3% for controlled.
METHODS: We attempted depression screening among workers using validated patient report outcomes(PROs) Thai version, TDI, LEAPS and WHOQOL-BREF. Voluntary participants recruitment as per IRB approval with consent informed obtained via convenient sampling. PROs scale reliability test using Cronbach’s Alpha correlation coefficient. Test score results were compared with that of civil servant participants as controlled. Statistical analysis employed independent t-test, score correlation employed Pearson correlation coefficient.
RESULTS: Overall 60 individuals, 30 each had regular salary income and non-regular income as compared with 30 civil servants with mean(SD) age in years of 30.4(19.6) vs 36.6(10.8). Other demographics, medical history collected were compared and not statistically significant different. The Cronbach’s alpha correlation coefficient for TDI, LEAPS and WHOQOL-BREF were 0.904,0.907 and 0.938 respectively. The PROs score of individuals vs controlled for total mean(SD) of TDI 18.10(9.98) vs 6.53(5.31) was statistically significant different, p=0.001. These scores suggestive of minor, mild to moderate depression with number(%) were 6(10%), 9(15%) and 4 (6.7%) vs controlled 1(3%), p=0.001 by independent t-test. Total mean(SD) of LEAPS 1.95(1.01) vs 4.60(4.55) suggestive of minimal, minor and moderate mental health insufficiency were significant different as compared with controlled with number(%) of 46 (75.0%), 11(18.5%),4(6.6%) vs 27(90.0%), 3(10%) and 0(0%) at p=0.001. The WHOQOL-BREF reflected a standardized score in mean(SD) with 59.96(15.86) vs 71.76(11.88), were statistically significant with p=0.001. TDI and LEAPS are highly correlated with Pearson correlation coefficient of 0.664 whereas TDI vs WHOQOL-BREF and LEAPS vs WHOQOL-BREF reflected Pearson correlation coefficient of -0.730 and -0.671 respectively.
CONCLUSIONS: This investigation employed validated Thai version of TDI, LEAPS and WHOQOL-BREF were robust, reliable with predicted incidence of mild- moderate depression could be as high as 25% as compared with 3% for controlled.
Conference/Value in Health Info
2025-09, ISPOR Real-World Evidence Summit 2025, Tokyo, Japan
Value in Health Regional, Volume 49S (September 2025)
Code
RWD8
Topic Subcategory
Data Protection, Integrity, & Quality Assurance
Disease
SDC: Mental Health (including addition)