Does Health Plan Enrollment Data Support Long-term Follow-up of Patients with Chronic Disease? Assessment of the Healthcare Integrated Research Database (HIRD®)

Author(s)

John J. Barron, PharmD, Malvika Venkataraman, MS, Michael Grabner, PhD, Katherine M. Harris, PhD, Vincent J. Willey, PharmD, Daniel C. Beachler, PhD.
Carelon Research, Wilmington, DE, USA.

Presentation Documents

OBJECTIVES: Duration of health plan enrollment is an important consideration in the design of studies using payer databases. We conducted a descriptive analysis of enrollment duration among commercial and managed Medicare members of a large US health plan. We compared enrollment duration by member characteristics and five chronic diseases: type 2 diabetes mellitus (T2DM), breast cancer (BC), heart failure (HF), multiple sclerosis (MS), and Alzheimer’s disease (ALZD).
METHODS: A retrospective analysis using payer claims from the Healthcare Integrated Research Database (HIRD®). Study members had an outpatient office visit for any reason or were newly diagnosed with any of the five conditions between 10/01/2016 and 09/30/2020. Index date was date of first office visit claim or first claim with chronic disease. We required enrollment for at least a year before index date. We calculated enrollment duration from index date through 09/30/2024. Enrollment duration was calculated in months by age categories (≤17, 18-44, 45-64, ≥65 years) and race/ethnicity, and reported as median (interquartile range) months.
RESULTS: A total of 11.7 million members had an office visit during the study period. Mean age varied by condition, ranging from 48 years (MS) to 83 years (ALZD); overall mean age was 39 years. Post-index enrollment duration was 38 months (14-80) among all members, with 36% enrolled for ≥5 years. Enrollment duration was similar for members with T2DM, BC, and MS, 44 (18-68), 48 (19-69) and 40 (16-67) months, respectively. Enrollment was shorter for those with HF, 35 (11-62) and ALZD, 30 (12-54) months. Enrollment duration varied by age, ≤17 - 47 (15-85), 18-44 - 31 (12-68), 45-64 - 39 (14-81) and ≥65 - 53 (19-93), and was longest for White non-Hispanics, 41 (15-83) and shortest for Asians, 35 (13-74) months.
CONCLUSIONS: Results show that large payer databases can support studies requiring longer follow-up periods.

Conference/Value in Health Info

2025-05, ISPOR 2025, Montréal, Quebec, CA

Value in Health, Volume 28, Issue S1

Code

RWD118

Topic

Real World Data & Information Systems

Topic Subcategory

Data Protection, Integrity, & Quality Assurance, Reproducibility & Replicability

Disease

No Additional Disease & Conditions/Specialized Treatment Areas

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