Does Health Plan Enrollment Data Support Long-term Follow-up of Patients with Chronic Disease? Assessment of the Healthcare Integrated Research Database (HIRD®)
Author(s)
John J. Barron, PharmD, Malvika Venkataraman, MS, Michael Grabner, PhD, Katherine M. Harris, PhD, Vincent J. Willey, PharmD, Daniel C. Beachler, PhD.
Carelon Research, Wilmington, DE, USA.
Carelon Research, Wilmington, DE, USA.
Presentation Documents
OBJECTIVES: Duration of health plan enrollment is an important consideration in the design of studies using payer databases. We conducted a descriptive analysis of enrollment duration among commercial and managed Medicare members of a large US health plan. We compared enrollment duration by member characteristics and five chronic diseases: type 2 diabetes mellitus (T2DM), breast cancer (BC), heart failure (HF), multiple sclerosis (MS), and Alzheimer’s disease (ALZD).
METHODS: A retrospective analysis using payer claims from the Healthcare Integrated Research Database (HIRD®). Study members had an outpatient office visit for any reason or were newly diagnosed with any of the five conditions between 10/01/2016 and 09/30/2020. Index date was date of first office visit claim or first claim with chronic disease. We required enrollment for at least a year before index date. We calculated enrollment duration from index date through 09/30/2024. Enrollment duration was calculated in months by age categories (≤17, 18-44, 45-64, ≥65 years) and race/ethnicity, and reported as median (interquartile range) months.
RESULTS: A total of 11.7 million members had an office visit during the study period. Mean age varied by condition, ranging from 48 years (MS) to 83 years (ALZD); overall mean age was 39 years. Post-index enrollment duration was 38 months (14-80) among all members, with 36% enrolled for ≥5 years. Enrollment duration was similar for members with T2DM, BC, and MS, 44 (18-68), 48 (19-69) and 40 (16-67) months, respectively. Enrollment was shorter for those with HF, 35 (11-62) and ALZD, 30 (12-54) months. Enrollment duration varied by age, ≤17 - 47 (15-85), 18-44 - 31 (12-68), 45-64 - 39 (14-81) and ≥65 - 53 (19-93), and was longest for White non-Hispanics, 41 (15-83) and shortest for Asians, 35 (13-74) months.
CONCLUSIONS: Results show that large payer databases can support studies requiring longer follow-up periods.
METHODS: A retrospective analysis using payer claims from the Healthcare Integrated Research Database (HIRD®). Study members had an outpatient office visit for any reason or were newly diagnosed with any of the five conditions between 10/01/2016 and 09/30/2020. Index date was date of first office visit claim or first claim with chronic disease. We required enrollment for at least a year before index date. We calculated enrollment duration from index date through 09/30/2024. Enrollment duration was calculated in months by age categories (≤17, 18-44, 45-64, ≥65 years) and race/ethnicity, and reported as median (interquartile range) months.
RESULTS: A total of 11.7 million members had an office visit during the study period. Mean age varied by condition, ranging from 48 years (MS) to 83 years (ALZD); overall mean age was 39 years. Post-index enrollment duration was 38 months (14-80) among all members, with 36% enrolled for ≥5 years. Enrollment duration was similar for members with T2DM, BC, and MS, 44 (18-68), 48 (19-69) and 40 (16-67) months, respectively. Enrollment was shorter for those with HF, 35 (11-62) and ALZD, 30 (12-54) months. Enrollment duration varied by age, ≤17 - 47 (15-85), 18-44 - 31 (12-68), 45-64 - 39 (14-81) and ≥65 - 53 (19-93), and was longest for White non-Hispanics, 41 (15-83) and shortest for Asians, 35 (13-74) months.
CONCLUSIONS: Results show that large payer databases can support studies requiring longer follow-up periods.
Conference/Value in Health Info
2025-05, ISPOR 2025, Montréal, Quebec, CA
Value in Health, Volume 28, Issue S1
Code
RWD118
Topic
Real World Data & Information Systems
Topic Subcategory
Data Protection, Integrity, & Quality Assurance, Reproducibility & Replicability
Disease
No Additional Disease & Conditions/Specialized Treatment Areas