OBJECTIVE: Remote monitoring platforms can enable patient centricity in routine care, thereby systematically bringing patient perspectives to the treatment experience. The objective of this study is to assess patient-reported outcomes and treatment preferences in a real-world treated oncology population, and how this information can be routinely gathered at point-of-care. METHODOLOGY: The patient cohort (n=275) was derived from users of PROmpt^®, an application for remote patient reporting and provider symptom management, employed in routine care in 30+ integrated cancer treatment centers. Patients were enrolled (1/8/19-11/1/21) at treatment initiation and provided with weekly surveys. Baseline characteristics assessed included frailty, patient quality-of-life (QoL) preferences, perception of cancer curability and treatment concerns. Results were descriptively assessed overall and stratified by solid versus hematologic malignancies, frailty and curability perception. Statistical differences were assessed using Pearson Chi-square, Likelihood Ratios and Linear-by-Linear associations.

RESULTS: With respect to frailty, the cohort was 63% fit, 22% intermediate, and 14% frail. 64% felt their cancer was curable. The majority (>90%) prioritized quality-of-life over length-of-life. Differences in QoL preference by fitness level were not statistically significant (98%, 88%, 82% respectively), although some directional preference towards QoL for fit patients was seen in linear-by-linear association. Results were also comparable between solid tumors and hematologic malignancies (90% vs 88% respectively) as well as by perception of curability vs non-curability of disease (88% vs 8=94%). Among concerns reported at baseline, most were pertained to understanding and selection of treatment, followed by cost and scheduling management, with no significant differences between solid tumors and hematologic malignancies. CONCLUSION: Overall results demonstrate the feasibility of gathering patient perspectives such as QoL preference, perceptions of curability, and treatment concerns in routine practice.While overall baseline differences did not vary significantly between groups, future research will explore changes in patient preferences and concerns over time as treatment progresses.