The Health-Related Quality of Life, Renal Dysfunction and Bladder Stone Odds Among Individuals With Spinal Cord Injury With Different Bladder Emptying Methods Surveyed Across China: An Exploratory Analyses From Two National Surveys
Author(s)
Fan Zhang, MSc1, Chengaxin Duan, MSc1, Runmin Liu, MBA2, Xiao Wen Luah, MSc3, Sijie Han, MSc2, Lu Tian, BSc4.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
1Beijing Health Economics Association, Beijing, China, 2Coloplast (China) Medical Device Ltd., Beijing, China, 3Coloplast A/S, Copenhagen, Denmark, 4China Association of Persons with Physical Disabilities, Beijing, China.
OBJECTIVES: This study aims to explore the health-relatedquality of life (HRQoL), as well as the odds of renal dysfunction and bladderstones, among community-dwelling Chinese individuals with spinal cord injury(SCI) using different bladder management methods.
METHODS: Two nationwide surveys were conducted acrossChina in 2020 (n=2,983) and 2023 (n=3,027). Respondents were categorized accordingto the respective bladder management methods: normal voiding, intermittentcatheterization (IC), transurethral indwelling catheterization (TIC),suprapubic indwelling catheterization (SIC), others (e.g. pads, bladderexpression) and mixed methods. HRQoL was assessed using SF-36 and reportedthrough Physical Health Composite (PHC) and Mental Health Composite (MHC)Scores. Exploratory multivariable logistic regression was conducted to identifythe odds ratio (OR) for bladder stone and renal dysfunction across bladdermanagement methods.
RESULTS: Survey respondents were predominantly male (aged45-46), paraplegic, with thoracic injuries, requiring assistance andwheelchairs. Respondents with normal voiding reported higher PHC and MHC scoresthan IC, TIC, SIC, others and mix methods (p<0.05). In 2020, IC usersreported higher PHC than TIC and SIC users (p<0.05), a similar butnon-significant trend was also observed in 2023. Respondents on TIC had higher oddsof bladder stones and renal dysfunction compared to those on IC, with significanceobserved only in 2020 data. Respondents on SIC showed significantly higher oddsof bladder stones and renal dysfunction compared to those on IC in both years.
CONCLUSIONS: Respondents using IC reported higher PHC scorescompared to those on TIC and SIC. Respondents on IC reported lower odds forbladder stone and renal dysfunction compared to respondents on TIC and SIC. Thesefindings underscore the need for patient-centered bladder management strategiesto optimize HRQoL and reduce the odds of complications such as bladder stoneand renal dysfunction.
METHODS: Two nationwide surveys were conducted acrossChina in 2020 (n=2,983) and 2023 (n=3,027). Respondents were categorized accordingto the respective bladder management methods: normal voiding, intermittentcatheterization (IC), transurethral indwelling catheterization (TIC),suprapubic indwelling catheterization (SIC), others (e.g. pads, bladderexpression) and mixed methods. HRQoL was assessed using SF-36 and reportedthrough Physical Health Composite (PHC) and Mental Health Composite (MHC)Scores. Exploratory multivariable logistic regression was conducted to identifythe odds ratio (OR) for bladder stone and renal dysfunction across bladdermanagement methods.
RESULTS: Survey respondents were predominantly male (aged45-46), paraplegic, with thoracic injuries, requiring assistance andwheelchairs. Respondents with normal voiding reported higher PHC and MHC scoresthan IC, TIC, SIC, others and mix methods (p<0.05). In 2020, IC usersreported higher PHC than TIC and SIC users (p<0.05), a similar butnon-significant trend was also observed in 2023. Respondents on TIC had higher oddsof bladder stones and renal dysfunction compared to those on IC, with significanceobserved only in 2020 data. Respondents on SIC showed significantly higher oddsof bladder stones and renal dysfunction compared to those on IC in both years.
CONCLUSIONS: Respondents using IC reported higher PHC scorescompared to those on TIC and SIC. Respondents on IC reported lower odds forbladder stone and renal dysfunction compared to respondents on TIC and SIC. Thesefindings underscore the need for patient-centered bladder management strategiesto optimize HRQoL and reduce the odds of complications such as bladder stoneand renal dysfunction.
Conference/Value in Health Info
2025-09, ISPOR Real-World Evidence Summit 2025, Tokyo, Japan
Value in Health Regional, Volume 49S (September 2025)
Code
RWD236
Topic Subcategory
Health & Insurance Records Systems
Disease
SDC: Injury & Trauma