Abstract

Objectives

Digital health programs have been suggested as one possible framework to improve health-related quality of life (HRQoL). This study investigates the impact of a digital health pharmacy interventions (DHPIs) on self-reported HRQoL and quality-adjusted life-years in patients with ischemic heart disease.

Methods

A 1-year follow-up randomized controlled trial was conducted from September, 2022 to August, 2023, at the Punjab Institute of Cardiology in Lahore. Adults with ischemic heart disease (IHD) (n = 332) were randomly allocated to either the intervention group (n = 166) or the control group (n = 166). The responses were evaluated using 2 validated questionnaires, namely, the SF-12 and EQ-5D-5L. The McNemar test, independent-sample t test, multivariate analysis of variance, and principal component analysis models were used to analyze the data. The P value less than .05 value was considered as a significant.

Results

The study results showed that 119 (48%) females and 129 (52.01%) males completed the 1 year’ follow-up study, and 36% were above 60 years old. The HRQoL of patients with ischemia in the intervention group showed a significant improvement over time with mean ± SD value of 30.81 ± 12.42 at baseline, whereas 38.94 ± 20.13 at 6 months and 43.53 ± 16.26 at 12 months. Moreover, DHPIs had a 75% impact on overall health, 97% on mental health, 91% on physical health, and 88% on social health among the patients with ischemia.

Conclusions

There is a significant improvement in HRQoL among patients with IHD, suggesting that the implementation of DHPIs may an effective strategy for management of IHD.