November 8: Practical Applications of Large Language Models for Real-World Evidence Generation and HEOR  - In Person at ISPOR Europe 2026
event-Short-Courses

November 8, 2026

Examine large language models (LLMs) for real-world evidence and HEOR

This course explores large language models (LLMs) from leading organizations such as OpenAI, Anthropic, Google, and Meta, with a focus on their application in real-world evidence (RWE) generation and HEOR. It introduces key technical concepts and considerations for responsible use in regulated environments.

Technical topics include:

  • LLM architecture, processing layers, and attention mechanisms
  • Embeddings, context windows, and hallucinations
  • Risk-based frameworks and model evaluation benchmarks
  • Practical considerations for applying LLMs in HEOR and RWE

This course includes tools and concepts that can be immediately applied, including:

  • Hands-on prompt engineering techniques
  • Use cases such as literature retrieval, PICO extraction, and data extraction
  • Summarizing tables and figures, automating captions, and generating code
  • Practical exercises using commercially available LLM tools
Upon completing this in-depth course, participants will gain the competencies needed to use LLMs responsibly for practical applications in RWE and HEOR, while remaining mindful of regulatory obligations. To participate in practical exercises, attendees are required to bring a personal laptop and have access to a personal or corporate LLM account with file upload functionality.

PREREQUISITE: General knowledge of chat-based LLMs (GPT, Claude, etc) is important. This is an intermediate course, and students should have prior knowledge of AI and have used chat based LLMs in a professional/work setting. 

Register Here

*Conference attendance is not required to attend an ISPOR Short Course. Separate registration is required for conference attendees.

LEVEL: Intermediate
TRACK: Methodological & Statistical Research

FACULTY MEMBERS

Manuel Cossio, MMed, MEng
Director of Business Development, Cytel Inc. 
Zürich, Switzerland and
AI Researcher, Universitat de Barcelona
Barcelona, Spain

Ben Bray, MD, MSc
Evidence Generation Lead
Lane Clark and Peacock LLP
London, England, UK

Schedule:

LENGTH: 4 Hours | Course runs 1 day

Sunday, 8 November 2026 | Course runs 1 Day
1:00pm-5:00pm Central European Time (CET)

Register Here

*Conference attendance is not required to attend an ISPOR Short Course. Separate registration is required for conference attendees.

Visit the ISPOR Europe 2026 Program page to view all short courses offered.

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